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Diagnostic Potential of Serum Circulating miRNAs for Endometriosis in Patients with Chronic Pelvic Pain.

Background: Endometriosis is a chronic gynecological condition marked by ectopic endometrial-like tissue, leading to inflammation, pain, and infertility. Diagnosis is often delayed by up to 10 years. Identifying non-invasive biomarkers …

Published: July 21, 2025, midnight
The Effect of Dienogest on Deep Endometriosis Nodules Involving the Recto-Sigmoid Colon: A Prospective Longitudinal Long-Term Study.

Objective: To assess the long-term effects of Dienogest on clinical complaints and nodule sizes in women affected by recto-sigmoid deep endometriosis (DE). Methods: This was a single-center longitudinal prospective observational …

Published: July 21, 2025, midnight
Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in ectopic endometriosis.

Endometriosis is often diagnosed late and presents significant challenges in clinical treatment. A comprehensive investigation of the cellular classification and composition of endometriosis is essential for studying its diagnosis and …

Published: July 18, 2025, midnight
Non-Hormonal Strategies in Endometriosis: Targets with Future Clinical Potential.

Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …

Published: July 17, 2025, midnight
Exploring the therapeutic potential of H1-antihistamines in endometriosis-A gene regulation-based perspective.

Recent studies emphasize the role of immune dysregulation and inflammation in endometriosis (ES). While hormonal therapy remains the primary treatment, emerging research is exploring synergistic approaches that target inflammation. In …

Published: July 17, 2025, midnight
Laparoscopic hysterectomy with intraoperative treatment of vaginal strictures: A case report.

There is limited data regarding management of vaginal strictures with a concurrent hysterectomy, in all realms, including pre-, intra- and postoperative care. A 44-year-old nulligravid woman with multiple vaginal strictures …

Published: July 14, 2025, midnight
Multiple lesions of endometriosis in the small intestine treated by the shaving technique: A case report.

A case is reported of endometriosis present in several areas of the small intestine, successfully treated by excision using the conservative technique of shaving the intestinal wall. A 30-year-old woman …

Published: July 13, 2025, midnight
Umbilical Endometriosis With Appendiceal Involvement: A Case Report.

Endometriosis is a common disease that affects women worldwide. While it is most commonly located in the pelvis, lesions may occur in other areas of the body. Concurrent umbilical and …

Published: July 7, 2025, midnight
Minilaparoscopic Versus Conventional Laparoscopic Hysterectomy: Insights from a Single-Center Retrospective Cohort Study with Legal Considerations.

Background and Objectives: We compared mini-laparoscopic and laparoscopic hysterectomy in terms of surgery duration, postoperative pain, conversion rate, blood loss, postoperative complications (Clavien-Dindo classification), and the length of hospital stay. …

Published: July 3, 2025, midnight
Exploring the Immune System's Role in Endometriosis: Insights Into Pathogenesis, Pain, and Treatment.

Endometriosis is a common gynecological condition that usually affects women during their reproductive years. The main goal of this narrative review is to understand the role of the innate and …

Published: July 1, 2025, midnight
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