Stage-Related Changes in TGF-β Isoforms in PBMC Culture Supernatants in Endometriosis: A Prospective Case-Control Study.
Endometriosis is a chronic inflammatory disease in which transforming growth factor-beta (TGF-β) has been implicated in immune dysregulation, extracellular matrix remodeling, and fibrosis. Data on baseline secretion of TGF-β isoforms …
Microbiota-metabolite axis in endometriosis: Pathogenic mechanisms and clinical implications.
Growing evidence highlights the role of microbiota, including those of the gut, reproductive tract, and endometrial tissue, as critical functional drivers in the pathogenesis of endometriosis (EM). Studies have revealed …
Effect of postoperative hormonal therapy on pain following endometriosis surgery: a retrospective cohort study.
Endometriosis is heterogeneous, and evidence for individualised postoperative management is limited. We assessed whether postoperative hormonal therapy exposure is associated with one-year changes in pain domains after first-time endometriosis surgery …
Associations between self-reported personal care products use and menstrual cycle length and regularity in a US digital cohort.
Personal care products (PCPs) may contain endocrine-disrupting chemicals (EDCs) that can impact menstrual health. Despite widespread usage, little is known about the associations of PCP usage, EDC avoidance, and menstrual …
Clinical Value of Circulating Endometrial Cells in the Diagnosis and Stratified Diagnosis of Endometriosis.
Background/Objectives: The diagnosis of endometriosis (EM) remains challenging due to the lack of a perfect diagnostic standard and the poor concordance between clinical symptoms and lesion severity. Although laparoscopy is …