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Clinical and endocrine effects of pharmacological therapy in endometriosis: a systematic review and meta-analysis.

Endometriosis, PCOS, adenomyosis, and dysmenorrhea are major illnesses. Hormonal as well as non-hormonal treatments were evaluated for COCs, progestins, GnRH analogues, LNG-IUS, relugolix, and adjunctive therapies. These treatments resulted in …

Published: April 1, 2026, midnight
Assessing endometrial microbiota in endometriosis: culturomics and sequencing analysis of receptive-phase tissue.

Endometriosis has been associated with alterations in the reproductive tract microbiota, yet studies focusing on the endometrial microbiome remain inconsistent, partly due to the low-biomass nature of this niche and …

Published: April 1, 2026, midnight
Evaluating Subtypes of Endometriosis in Rhesus Macaques (Macaca mulatta) Using Clinical Findings and Immunohistochemistry.

Endometriosis is defined as endometrial tissue outside of the uterus. It is a debilitating, complex, and underdiagnosed condition, impacting approximately 10%-15% of reproductive-aged women worldwide. Endometriosis is associated with chronic …

Published: April 1, 2026, midnight
Synergistic effects of melatonin and dienogest on pain relief in endometriosis: a randomized controlled trial.

Endometriosis affects 5-10% of reproductive-aged women and is characterized by chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility. Standard hormonal therapies, such as dienogest, effectively manage symptoms, but are often associated …

Published: March 31, 2026, midnight
Demographic and hematological differences between endometriosis and menorrhagia in Saudi women: A retrospective observational study of 946 patients.

Endometriosis and menorrhagia are prevalent gynecological conditions with overlapping symptoms, yet comparative data from Middle Eastern populations remain scarce. We aimed to comprehensively characterize demographic and hematological differences between these …

Published: March 28, 2026, midnight
Shared Pathophysiology and Early Detection Biomarkers in Endometriosis and Polycystic Ovary Syndrome (PCOS): Opportunities for AI-Enabled Screening.

Endometriosis and polycystic ovary syndrome (PCOS) are common, multifactorial gynecological disorders shaped by endocrine imbalance, immune dysfunction, metabolic disruption, genetic susceptibility, and environmental exposures. Despite their major contribution to infertility …

Published: March 28, 2026, midnight
Integrating Metabolic and MicroRNA Profiling to the Diagnostics of Endometriosis: A Pilot Study.

Endometriosis affects a large number of women of reproductive age, and its pathogenesis is still unclear. It causes severe chronic pelvic pain, which is often misdiagnosed as irritable bowel syndrome, …

Published: March 27, 2026, midnight
Contraceptive-Induced Weight Gain-Myth and Reality Review.

The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane …

Published: March 27, 2026, midnight
Italian Expert Consensus on Women's Nutrition Across the Life Course: A Modified Delphi Study.

Objective: Nutrition is a key determinant of women's health across all life stages. Clinical practice remains heterogeneous because of lack of evidence and non-homogeneous guidelines. Despite growing research on micronutrient …

Published: March 26, 2026, midnight
Catheter-Directed Sclerotherapy Versus Ovarian Cystectomy for Unilateral Ovarian Endometrioma: A Pilot Randomized Controlled Trial.

Background: Ovarian cystectomy is standard treatment for endometrioma but is associated with decreased ovarian reserve. Catheter-directed sclerotherapy (CDS) is an ovary-sparing image-guided alternative; however, supporting evidence comprises retrospective comparative and …

Published: March 25, 2026, midnight
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