The microbiome-inflammasome axis in endometriosis-associated chronic pelvic pain: mechanisms and therapeutic opportunities from an immunological perspective.
Endometriosis (EMs) is increasingly recognized as a chronic inflammatory disease in which innate immune dysregulation plays an important role. Its immunopathological features include macrophage polarization imbalance, with M1-skewed activation in …
NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.
Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …
Patient- and disease-related characteristics to anticipate segmental resection for isolated rectal endometriosis: a multicenter prospective study.
To identify predictors for segmental resection in patients with an isolated rectal endometriotic nodule (i.e. involvement of at least the muscular layer in depth and up to 15cm to the …