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Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Non-Hormonal Endometriosis Therapy.

Previous studies show that orphan nuclear receptor 4A1 (NR4A1) regulated endometriotic cell growth, survival, estrogen receptor β (ERβ), mTOR signaling and fibrosis. NR4A2 is also expressed in epithelial and stromal …

Published: Sept. 26, 2025, midnight
Di-(2-ethylhexyl) phthalate induces endometriosis by modulating IGF-1 m6A methylation via the intestinal Odoribacter-butyric acid axis in female rats.

Endometriosis, a complex gynecological disorder characterized by aberrant growth of endometrial tissue outside the uterine cavity, poses a significant challenge to women's health. Emerging evidence implicates environmental pollutants, particularly di-(2-ethylhexyl) …

Published: Sept. 23, 2025, midnight
Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis.

To investigate the associations between oxidative DNA damage biomarkers [levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), telomere length (TL), human telomerase reverse transcriptase (hTERT), telomerase activity (TA) and polymorphisms of human 8-oxoguanine glycosylase …

Published: Sept. 4, 2025, midnight
miR-4669 in Adenomyosis Boosts EMT via M2 Macrophages - BIOENGINEER.ORG

miR-4669 in Adenomyosis Boosts EMT via M2 Macrophages BIOENGINEER.ORG

Published: Aug. 27, 2025, 5:19 a.m.
AARS1 promotes endometriosis progression by promoting the lactylation of Snail1.

The widely accepted theory of endometriosis posits that endometriosis stems from the translocation of endometrial tissue through the fallopian tubes into the abdominal cavity. However, the exact pathogenesis and critical …

Published: Aug. 15, 2025, midnight
C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis.

Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic …

Published: Aug. 8, 2025, midnight
Ovum Launches with $1.7M Funding to Develop AI-Powered Women’s Health Platform - Femtech Insider

Ovum Launches with $1.7M Funding to Develop AI-Powered Women’s Health Platform Femtech Insider

Published: Aug. 7, 2025, 7:33 a.m.
Ovum Launches with $1.7m Funding to Develop AI-Powered Women’s Health Platform - Femtech Insider

Ovum Launches with $1.7m Funding to Develop AI-Powered Women’s Health Platform Femtech Insider

Published: Aug. 7, 2025, 7:08 a.m.
YC’s Fall 2025 Startup Requests: What They Signal for Women’s Health Innovation - Femtech Insider

YC’s Fall 2025 Startup Requests: What They Signal for Women’s Health Innovation Femtech Insider

Published: Aug. 6, 2025, 8:31 a.m.
Insights into the Molecular Mechanisms and Signaling Pathways of Epithelial to Mesenchymal Transition (EMT) in the Pathophysiology of Endometriosis.

Endometriosis is a disease characterized by the presence of endometrial glands and stroma outside of the uterine corpus, often clinically presenting with pain and/or infertility. Ectopic lesions exhibit features characteristic …

Published: Aug. 1, 2025, midnight
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