Endometriosis (EM) is driven by immune dysregulation and macrophage dysfunction, yet the underlying mechanisms remain unclear. Here, metabolomic profiling revealed excessive itaconate accumulation in EM lesions, primarily due to elevated …
This study aims to demonstrate that Andrographolide, an herbal immunostimulant, can influence M1 macrophages to inhibit inflammation, including the growth of endometriosis caused by inflammation. This study evaluates the effects …
Endometriosis(EMS) symptoms, progression, and onset are all linked to the patient's immune system dysfunction. Research on immune cells and their molecular mechanisms has long been a prime focus of EMS …
Endometriosis and links to miscarriage/ectopic pregnancies Contemporary OB/GYN
Endometriosis involves ectopic endometrial tissue outside the uterus, commonly in the pelvis but sometimes affecting organs like the urinary tract, gastrointestinal system, and respiratory tract. Abdominal wall endometriosis (AWE) is …
Endometriosis (EM) is a chronic inflammatory disease that affects ∼10% of women during reproductive age. It is characterised by ectopic (ECT) growth of endometrial-like tissue mainly in the pelvic cavity. …
Endometriosis (EMs) is a common chronic inflammatory gynecological disorder. But the exact pathogenetic mechanism of the disease is not clear, with some theories proposing that the disease is caused by …
Oskari Heikinheimo explains link of endometriosis and higher risks of miscarriage, ectopic pregnancy Contemporary OB/GYN
Transmembrane protein TMEM119 has been implicated in tumor progression (e.g., ovarian cancer), but its role and underlying mechanism in ovarian endometriosis (EM) remain elusive. Thus, this study aimed to investigate …
Endometriosis is a chronic, hormone-dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, …