To explore the material basis and network mechanism of the Guizhi Fuling pills in the treatment of endometriosis and endometrial polyps based on network pharmacology and machine learning. The effective …
Decidualization of endometrial stromal cells involves significant morphological and functional changes in which alpha-smooth muscle actin (αSMA) expression decreases. Meflin, a glycosylphosphatidylinositol-anchored protein, suppresses αSMA expression and inhibits fibrosis in …
Endometriosis is an estrogen-dependent disorder influenced by dysregulated steroidogenesis, oxidative stress, and inflammation. Bisphenol A (BPA), a common endocrine disruptor, has been associated with reproductive dysfunction, but its developmental impacts …
Endometriosis is underpinned by dysfunctional immune responses resulting in failure to clear ectopic endometrial lesions from the peritoneal cavity. The pelvic milieu comprising immature dendritic cells, dysfunctional cytotoxic lymphocytes, and …
Diaphragmatic endometriosis is a rare and often underrecognized manifestation of extrapelvic endometriosis that may lead to severe complications such as diaphragmatic rupture or herniation. We report the case of a …
Endometriosis has been associated with alterations in the reproductive tract microbiota, yet studies focusing on the endometrial microbiome remain inconsistent, partly due to the low-biomass nature of this niche and …
Endometriosis is defined as endometrial tissue outside of the uterus. It is a debilitating, complex, and underdiagnosed condition, impacting approximately 10%-15% of reproductive-aged women worldwide. Endometriosis is associated with chronic …
Endometriosis is a prevalent inflammatory condition characterised by the presence of endometrial-like tissue outside the uterus and is associated with significant challenges, including diagnostic delays and continued reliance on laparoscopy. …
The endometrium is a highly dynamic and complex tissue lining the uterus, playing a central role in reproductive health. Despite its importance, the pathogenesis of many benign endometrial disorders remains …
Endometriosis is a common gynecological disorder affecting women of reproductive age, often leading to chronic pain, reduced quality of life, and infertility. It is characterized by ectopic endometrial growth within …