Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.
Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …
Clinically Validated Leptin Receptor as a Target for Liposomal Delivery of Metformin in Endometriosis Therapy.
Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited …
Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.
Endometriosis is a chronic systemic disease affecting ~10% of women, yet its genetic basis and molecular mechanisms remain poorly understood. Hence, here we conducted a genome-wide association study of endometriosis …
Is endometriosis associated with poor sleep quality? A meta-analysis.
BackgroundEndometriosis is a hormone-driven systemic inflammatory condition characterized by endometrial-like lesions which grow throughout the body affecting up to 15% of women worldwide with symptoms including chronic pain, infertility, and …
Performance of Nonaugmented Routine Pelvic Ultrasound for Deep Endometriosis Using Static 2024 SRU Consensus Criteria: A Multireader Study.
To decrease the existing diagnostic delay of pelvic endometriosis, the Society of Radiologists in Ultrasound (SRU) has proposed consensus criteria using augmented pelvic ultrasound (APU) technique and reporting guidelines based …
Clear cell carcinoma developed on hepatic endometriosis: a case report and review of the literature.
Endometriosis is a chronic estrogen-dependent disorder that is generally localized in the pelvis affecting up to 10% of women in the reproductive age. Extra-pelvic locations are estimated to 9% of …