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Hyperestrogenic imprinting and developmental origins of endometriosis and adenomyosis.

The pathogenesis of endometriosis and adenomyosis remains incompletely understood, and a notable gap persists between the reported heritability and the disease variation explained by identified susceptibility loci. In this manuscript, …

Published: Aug. 10, 2026, midnight
Beyond the Mass Effect: Decoupling Endometrioma Size and Bilaterality from Ovarian Reserve Depletion.

Ovarian endometriomas are commonly assessed according to cyst size and laterality, anatomical features that have long been regarded as indicators of disease severity and potential ovarian compromise. Consequently, these characteristics …

Published: Aug. 9, 2026, midnight
Phthalate exposure and human reproductive health: an epidemiological review.

Plastics are ubiquitous in the environment and are widely used in food packaging, medicine, agriculture, construction and other sectors. However, the plasticizers they contain pose a substantial threat to environmental …

Published: Aug. 9, 2026, midnight
Harnessing diet to modulate inflammation and symptom progression in endometriosis.

Endometriosis (EMS) is an estrogen-dependent inflammatory disease affecting 10% of reproductive-age women, with up to 50% experiencing infertility. As primary care providers (PCPs) are often the first point of care, …

Published: Aug. 7, 2026, midnight
Residual hemostatic material (Surgicel) mimicking endometriosis: a case report of gossypiboma.

Gossypiboma, the unintentional retention of surgical materials, is a rare but significant postoperative complication. While most of the literature focuses on retained sponges, absorbable hemostatic agents such as Surgicel may …

Published: Aug. 7, 2026, midnight
TREM2 Deficiency Attenuates Endometriosis Progression by Inhibiting M2 Polarization of SpMs and Suppressing SIRPα to Enhance Phagocytosis.

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS patient …

Published: Aug. 5, 2026, midnight
Recent insights in pathogenesis of endometriosis with focus on gut microbiota.

EMs is a chronic, estrogen-dependent systemic inflammatory disorder defined by the ectopic implantation of endometrial glands and stroma and is frequently associated with dysmenorrhea, chronic pelvic pain, infertility, and substantial …

Published: Aug. 4, 2026, midnight
A Mouse Model of Endometriosis Using Ex Vivo Cy5.5 Dye-Doped Silica Nanoparticle Labeling for Lesion Visualization.

Endometriosis is a common gynecological disorder characterized by the growth of endometrial-like tissue outside the uterine cavity, leading to chronic inflammation, pelvic pain, and infertility. Reliable mouse models are essential …

Published: Aug. 4, 2026, midnight
Microplastics and female infertility: reproductive toxicity and underlying mechanisms.

In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …

Published: Aug. 3, 2026, midnight
Dietary and Environmental Exposure to Toxic Elements in Endometriosis: A Missing Piece of the Etiological Puzzle?

Background/Objectives: Endometriosis is a chronic estrogen-dependent disease with a complex and incompletely understood etiology. Environmental exposure to toxic elements, including cadmium, lead, mercury, and arsenic, may contribute to its development …

Published: Aug. 2, 2026, midnight
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