Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting ~10% of reproductive-age women. It is underdiagnosed, with delays of 5-12 years. Symptoms include dysmenorrhea, chronic pelvic pain, dyspareunia, dyschezia, dysuria, fatigue, …
Patients with endometriosis have greater risk of infertility, which is associated with compromised ovarian function. Dysfunction in follicular granulosa cells and hyperactivation of oestrogen receptor beta (ERβ) are evident in …
Short-Term Vaginal Estrogen Therapy Does Not Increase Risks of Endometrial Cancer Recurrence The ASCO Post
Vaginal estrogen therapy not associated with increased risk of endometrial cancer recurrence Contemporary OB/GYN
Vaginal estrogen therapy not linked to cancer recurrence in survivors of endometrial cancer Medical Xpress
Is Vaginal Estrogen Safe After Endometrial Cancer? Medscape
Vaginal estrogen therapy is safe for young endometrial cancer survivors, study finds News-Medical
Vaginal Estrogen Safe for Endometrial Cancer Survivors Mirage News
We investigated whether ovarian endometriomas uniformly express functional FSH receptors (FSHR) and respond to FSH by activating transcriptional programs that drive aromatase and steroid hormone production. Endometrioma cyst capsules were …
Female reproductive disorders represent a major global health challenge. Despite their clinical heterogeneity, these conditions share core pathological mechanisms including oxidative stress, chronic inflammation, hormonal imbalance, metabolic dysfunction, extracellular matrix …