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Microbiome in women with endometriosis and the in vitro effects of Lactobacillus reuteri on human endometrium.

Endometriosis (EMS) is a chronic inflammatory disorder affecting ~10% of reproductive-age women, with increasing evidence implicating the microbiome in its pathogenesis through immunomodulation and estrogen metabolism. This study investigated microbiome …

Published: May 6, 2026, midnight
Curcumin attenuates uterine pain in mice through suppression of neuroinflammation in the DRG and spinal cord.

Uterine pain associated with labor, dysmenorrhea, or endometriosis is often driven by inflammation, which enhances nociceptive signaling and contributes to hyperalgesia. Although nonsteroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids are commonly …

Published: May 6, 2026, midnight
Differential Antioxidant Capacities of Human Endometriotic and Endometrial Cell Models Under H2O2 Exposure.

Endometriosis is associated with oxidative stress and debilitating symptoms, yet its pathophysiology remains incompletely understood, and current treatments are still limited. In this study, oxidative stress responses were compared in …

Published: May 5, 2026, midnight
Interpretations of Menstrual Blood Appearance and Diagnostic Potential Among Social Media Users: Cross-Sectional Mixed Methods Social Media Listening Study.

Menstruation has long been framed primarily as a hygiene issue, with mainstream products and public messaging emphasizing concealment and disposal of menstrual blood (MB). This has contributed to a culture …

Published: May 4, 2026, midnight
Peer Support in Online Women's Health Communities: Mixed Methods Formative Analysis of Reddit Discourse.

Stigmatized women's health issues, such as polycystic ovary syndrome (PCOS) and endometriosis, are often marginalized or dismissed in traditional clinical settings. This drives individuals to seek peer support in anonymous …

Published: May 4, 2026, midnight
Visual tubal patency tests for tubal occlusion and hydrosalpinx.

Around 18% to 33% of couples with infertility present with tubal occlusion (blocked or damaged fallopian tubes) or hydrosalpinx (fluid-filled tubes). Diagnostic laparoscopy (keyhole surgery) with chromopertubation (methylene blue dye …

Published: May 4, 2026, midnight
Electroacupuncture ameliorates Endometriosis-Associated ovarian dysfunction by activating Nrf2 pathway to upregulate GPX4 function and inhibiting ferroptosis.

Endometriosis (EMs) is a common cause of ovarian dysfunction and infertility, closely linked to iron overload-induced oxidative stress and ferroptosis. While electroacupuncture (EA) has shown promise in treating reproductive disorders, …

Published: May 3, 2026, midnight
Reduced type 2 epithelial-mesenchymal transition serves as a risk factor for the progression from endometriosis to endometriosis-associated ovarian cancer.

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully …

Published: May 1, 2026, midnight
miR-769-5p inhibits cellular behaviors associated with endometriosis progression by directly targeting follistatin in vitro.

The pathogenesis of endometriosis (EM) remains intricate and multifactorial. This study aimed to investigate the biological functions of microRNA-769-5p (miR-769-5p) in an in vitro model of EM. Serum was obtained …

Published: April 30, 2026, midnight
Clinically Validated Leptin Receptor as a Target for Liposomal Delivery of Metformin in Endometriosis Therapy.

Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited …

Published: April 29, 2026, midnight
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