Latest Articles

Aetiology of pelvic neuropathies in women: a narrative review.

Pelvic neuropathy is an under-recognised contributor to chronic pelvic pain in women, yet a structured overview of its identifiable causes has been lacking. In this narrative review we searched PubMed, …

The microbiome-inflammasome axis in endometriosis-associated chronic pelvic pain: mechanisms and therapeutic opportunities from an immunological perspective.

Endometriosis (EMs) is increasingly recognized as a chronic inflammatory disease in which innate immune dysregulation plays an important role. Its immunopathological features include macrophage polarization imbalance, with M1-skewed activation in …

Integrative analysis and experiment validation of SLC12A8 as a biomarker for the malignant transition from endometriosis to endometriosis associated ovarian cancer.

Endometriosis (EM) is a chronic inflammatory, estrogen‑dependent benign gynecological disorder. A subset of patients with EM may subsequently develop endometriosis‑associated ovarian cancer (EAOC), implying a biological continuum between these two …

Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review.

This systematic review aimed to explore the application and effectiveness of transperineal ultrasound as a diagnostic tool for evaluating pelvic floor musculature (PFM) dysfunction in patients with chronic pelvic pain …

Living with adenomyosis and involuntary childlessness: a qualitative interview study.

Adenomyosis is a chronic gynecological condition associated with pain, abnormal uterine bleeding, and impaired fertility. However, little is known about the psychosocial experiences and coping strategies of individuals with adenomyosis …

The importance of power in photobiomodulation: a systematic review and meta-analysis of high-intensity laser therapy.

Low-level laser therapy (LLLT; ≤ 0.5 W) is guideline-recommended in the United States for shallow-tissue oral mucositis and other superficial pathologies but has generally failed in trials for deeper tissue …

The new WHO infertility guideline: A universal right to equitable, evidence-based fertility care.

The WHO 'Guideline for the prevention, diagnosis and treatment of infertility' heralds a significant global shift towards recognizing infertility as a medical condition requiring prevention, diagnosis, treatment and policy support. …

Chronic Endometrial Degeneration (CED): an international expert recommendation to replace the term 'endometrosis' in mares.

The term 'endometrosis', coined in 1992 to describe chronic degenerative changes of the equine endometrium, is descriptively imprecise and readily confused with 'endometritis' and the human gynaecological condition 'endometriosis'. A …

Inflammation-Targeted Endometriosis Research Needs Pain, Mood, and Fertility-Priority Outcomes.

Gendered Illnesses and Embodied Knowledge: A Phenomenological Body-Mapping Study of Endometriosis.

Endometriosis, a chronic health condition primarily associated with women, is not just a physical experience but is an invisible, gendered illness deeply intertwined with societal narratives that often overlook women's …