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Endometriosis in Carriers of a Pathogenic Variant in BRCA1 or BRCA2: A Descriptive Analysis of a Large Multicentral BRCA Carrier Cohort.

Background: Endometriosis affects an estimated 10% of reproductive-aged women and is associated with increased ovarian cancer risk. While BRCA1/2 mutations are established risk factors for ovarian cancer, their association with …

Published: Dec. 1, 2025, midnight
The overlooked link between reproductive system disorders and depression: a cohort study in 2 million women.

Depression rates are higher in women, especially during periods of hormonal fluctuation. Reproductive system disorders (RSDs), which often disrupt hormonal balance, may contribute to this mental health burden. Despite their …

Published: Nov. 21, 2025, midnight
Global prevalence of adenomyosis and endometriosis: a systematic review and meta-analysis.

The objective of this meta-analysis is to provide a comprehensive and up-to-date assessment of the prevalence of endometriosis and adenomyosis, addressing the limitations of existing research data and evaluating the …

Published: Nov. 19, 2025, midnight
Adenomyosis in patients with rheumatic diseases: a cross-disciplinary clinical observation.

Autoimmune and inflammatory rheumatic diseases (RDs) are more prevalent in women and often affect gynecological health. Particularly, heavy menstrual bleeding (HMB) and dysmenorrhea are more common in patients with RD. …

Published: Nov. 18, 2025, midnight
How We Can Optimize Dysmenorrhea Treatment: Real-World Results from a Cross-Sectional, Multi-Center Study.

Dysmenorrhea is a common and disabling condition in women. We investigate the prevalence of endocrine dysmenorrhea treatment (EDT) and the use of pain medication in dysmenorrhea patients without surgically treated …

Published: Nov. 17, 2025, midnight
Association between serum carotenoids and risk of endometriosis evidence from NHANES data.

Endometriosis is a prevalent gynecological disorder, with its pathogenesis potentially linked to oxidative stress. Carotenoids, as natural antioxidants, may play a role in its prevention. This study aimed to investigate …

Published: Nov. 10, 2025, midnight
Inpatient Endometriosis Care in Germany: Hospital Caseloads and their Spatial Distribution.

Endometriosis is a chronic gynaecological disease with an estimated prevalence of 10-15%. The German guideline provides evidence-based recommendations for diagnosis and treatment, but care provided is inadequate care due to …

Published: Nov. 3, 2025, midnight
Chronic Pelvic Pain Syndrome in Women: Clinical Covariates and Comorbidity Patterns.

Chronic pelvic pain syndrome (CPPS) in women is a debilitating condition with a high prevalence (5-25%), yet its etiology remains unclear. This prospective observational study aimed to identify clinical and …

Published: Nov. 2, 2025, midnight
Epidemiology of endometriosis based on real-world data in Japan.

Considering the progressively delayed age of pregnancy, what is the current epidemiology of endometriosis in Japan, including its prevalence, incidence and medication patterns, as revealed by a large-scale, real-world dataset?

Published: Nov. 2, 2025, midnight
Reframing Endometriosis: Interplay of NETs, Macrophages, and Lymphocytes at the Crossroads of Disease Progression, Infertility, and Malignant Transformation.

Endometriosis (ENDO) is a painful, chronic gynecological disease widely affecting women globally. While traditionally classified as a hormonal disorder, ENDO is now increasingly recognized as a multifaceted immune-mediated syndrome driven …

Published: Oct. 29, 2025, midnight
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