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Chronic Pelvic Pain Syndrome in Women: Clinical Covariates and Comorbidity Patterns.

Chronic pelvic pain syndrome (CPPS) in women is a debilitating condition with a high prevalence (5-25%), yet its etiology remains unclear. This prospective observational study aimed to identify clinical and …

Published: Nov. 2, 2025, midnight
Epidemiology of endometriosis based on real-world data in Japan.

Considering the progressively delayed age of pregnancy, what is the current epidemiology of endometriosis in Japan, including its prevalence, incidence and medication patterns, as revealed by a large-scale, real-world dataset?

Published: Nov. 2, 2025, midnight
Reframing Endometriosis: Interplay of NETs, Macrophages, and Lymphocytes at the Crossroads of Disease Progression, Infertility, and Malignant Transformation.

Endometriosis (ENDO) is a painful, chronic gynecological disease widely affecting women globally. While traditionally classified as a hormonal disorder, ENDO is now increasingly recognized as a multifaceted immune-mediated syndrome driven …

Published: Oct. 29, 2025, midnight
Global, regional, and national burden and trends of endometriosis, 1990-2021: an analysis of the global burden of disease study 2021 and forecast to 2050.

Endometriosis is highly prevalent but remains under-researched. This study, using the latest data, aims to provide a comprehensive assessment of the burden of endometriosis on a global scale.

Published: Oct. 28, 2025, midnight
The association between HPV infection and endometriosis: Risk and fertility outcomes.

While infections have been implicated in endometriosis pathogenesis, the role of human papillomavirus (HPV) remains unclear. This study combined a meta-analysis of seven studies with a case-control study ( n …

Published: Oct. 25, 2025, midnight
The effect of phytoestrogens and PAHs on endometriosis and the involvement of gut microbiota, inflammation, and molecular targets.

Endometriosis is a common estrogen-dependent inflammatory disease, yet its complex etiology is not fully understood. Endocrine Disrupting Chemicals (EDCs) exposure disrupts human reproduction, but studies on mixed EDCs and endometriosis …

Published: Oct. 15, 2025, midnight
Selective Appendectomy in Patients Undergoing Minimally Invasive Surgery for Endometriosis: A Retrospective Cohort Study.

Background/Objectives: Endometriosis is a chronic inflammatory systemic disease that commonly affects bowel structures, including the appendix, where it may mimic or coexist with chronic appendicitis. Visual inspection alone often fails …

Published: Oct. 15, 2025, midnight
Symptom tracking for endometriosis: a systematic review protocol for mobile applications focused on content, inclusivity and features.

Endometriosis is a chronic gynaecological condition affecting 2%-10% of women worldwide, often leading to severe pain, organ dysfunction and infertility. Despite its prevalence, diagnosis is frequently delayed, and treatment options …

Published: Oct. 10, 2025, midnight
Prevalence of gynecologic disorders in women with symptomatic pelvic venous disorders.

The diagnosis of symptomatic pelvic venous insufficiency (PVI) in women is complicated when concomitant gynecologic disorders are present. The purpose of this investigation is to determine the prevalence of concomitant …

Published: Oct. 7, 2025, midnight
Endometriosis-related infertility in China: analysis of the global burden of disease study 2021.

Utilizing the Global Burden of Disease (GBD) 2021 dataset, this study analyzed temporal trends (1990-2021) and age-period-cohort patterns of endometriosis-related infertility burden in China versus globally. By employing joinpoint regression …

Published: Oct. 7, 2025, midnight
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