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[Pain medicine aspects of the updated S2k guideline "Diagnosis and treatment of endometriosis"].

The scheduled update of the S2k guideline "Diagnosis and treatment of endometriosis", published by the Association of the Scientific Medical Societies in Germany (AWMF; registry number 015/045), was released on …

Published: June 11, 2026, midnight
ENDO-GYM: A holistic approach with pelvic floor physiotherapy and Yoga for endometriosis pain relief.

To retrospectively evaluate the impact of ENDO-GYM Program, which combined Yoga practice and pelvic floor physiotherapy (PFP), on women with ultrasound and/or post-operative histological diagnosis of endometriosis pain resistant to …

Published: June 11, 2026, midnight
The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.

Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …

Published: June 10, 2026, midnight
Endometriosis-associated Pain: Mechanism, Neuroimmune Signature, and Translational Precision Strategies.

Endometriosis affects approximately 10% of reproductive-aged women worldwide and is a leading cause of chronic pelvic pain. Despite its high prevalence and substantial socioeconomic burden, the mechanisms underlying endometriosis-associated pain …

Published: June 10, 2026, midnight
Role of hormonal therapies in endometriosis: balancing efficacy and safety.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder requiring long-term management strategies that balance efficacy with systemic safety. Although hormonal therapies remain the cornerstone of treatment, the optimal degree of estrogen …

Published: June 10, 2026, midnight
Molecular Insights Into Endometriosis for Early Detection and Therapeutic Targets.

Endometriosis is a hormone-dependent chronic inflammatory disease associated with pain and infertility, remains diagnostically and therapeutically challenging due to its multifactorial nature. Molecular mechanisms of the dynamic changes during disease …

Published: June 10, 2026, midnight
Harnessing the murine inner cell mass mechanical environment enhances derivation of in vitro nascent primitive endoderm precursor cells.

Stem cell-based models resembling murine blastocysts represent a useful system to investigate subsequent developmental processes. While existing cell lines derived from epiblast and trophectoderm can be aggregated to form 'blastoids', …

Published: June 10, 2026, midnight
Interpretable machine learning for endometriosis classification: a rule-based approach.

Endometriosis is a chronic gynecological disease characterized by the growth of endometrial-like tissue outside the uterus, leading to pelvic pain, infertility, and other major health complications. Though some studies have …

Published: June 10, 2026, midnight
Multiple recurrences of postmenopausal endometriosis associated with estrogen pellet therapy: clinical implications for hormone therapy and surgical management.

To challenge the perception that endometriosis uniformly regresses after menopause by presenting the case of repeated, pathology-confirmed symptomatic recurrences spanning two decades after menopause, and to emphasize key considerations for …

Published: June 9, 2026, midnight
Identification and diagnostic potential of pyroptosis-related genes in endometriosis: A novel bioinformatics analysis and validation.

Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic endometrial growth. This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs.

Published: June 9, 2026, midnight
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