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Per- and polyfluoroalkyl substances exposure and endometriosis risk: Evidence from epidemiologic, network toxicology, and molecular docking.

Although per- and polyfluoroalkyl substances (PFAS) exposure has been linked to endometriosis, this association remains controversial, and the underlying mechanisms are unclear. This study aimed to investigate this relationship and …

Published: Nov. 19, 2025, midnight
The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies.

Mitophagy is a catabolic mechanism that selectively degrades damaged mitochondria and precisely modulates mitochondrial content, thereby maintaining intracellular homeostasis under stress conditions. To date, most reviews on mitophagy have predominantly …

Published: Nov. 18, 2025, midnight
The effect of infertility-related stress on fertility-related quality of life in reproductive-age married women with endometriosis: the mediating role of family resilience.

This study investigated fertility-related quality of life among married women of reproductive age (20-45 years) with endometriosis-associated infertility, focusing on the mediating role of family resilience between infertility-related stress and …

Published: Nov. 16, 2025, midnight
Association between serum carotenoids and risk of endometriosis evidence from NHANES data.

Endometriosis is a prevalent gynecological disorder, with its pathogenesis potentially linked to oxidative stress. Carotenoids, as natural antioxidants, may play a role in its prevention. This study aimed to investigate …

Published: Nov. 10, 2025, midnight
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis - Nature

Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis Nature

Published: Nov. 4, 2025, 7:16 p.m.
Psychoneuroendocrine Associations with Momentary Pelvic Pain in Endometriosis.

Endometriosis is a gynecological condition which often causes chronic or recurrent pelvic pain (CPP). The disease can thereby impose a significant burden on affected individuals and their romantic relationships. Existing …

Published: Nov. 4, 2025, midnight
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis.

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify …

Published: Nov. 4, 2025, midnight
Psychosocial Factors and Disease Localization as Independent Predictors of Sexual Dysfunction in Women with Endometriosis.

Background: This study examines the impact of endometriosis on sexual function, focusing on disease localization, pain severity, and psychosocial factors. It integrates the rASRM and Enzian classification systems to explore …

Published: Nov. 2, 2025, midnight
FAK-dependent activation of src family kinase member BLK contributed to endometrial fibrosis via endoplasmic reticulum stress - Cell & Bioscience

FAK-dependent activation of src family kinase member BLK contributed to endometrial fibrosis via endoplasmic reticulum stress Cell & Bioscience

Published: Oct. 31, 2025, 9:23 a.m.
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
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