Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …
Endometriosis is a chronic condition where tissue resembling the uterine lining grows elsewhere in the pelvis, often causing pain, infertility, and inflammation. For decades, textbooks and research papers have described …
Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …
To investigate the therapeutic potential of phytoestrogens in the management of endometriosis and to elucidate their mechanisms of action based on current preclinical and clinical evidence.
Rheumatoid arthritis (RA) is a chronic autoimmune disease. An increasing body of evidence indicates that hormones, particularly estrogen, play a significant role in RA. To date, no bibliometric studies have …
Endometriosis (ENDO) is a chronic, estrogen-dependent condition affecting over 190 million females worldwide. Characterized by cyclic pelvic pain, infertility, and systemic inflammation, its symptoms profoundly impact quality of life, interfering …
Endometriosis, affecting 6%-10% of reproductive-age women, causes chronic pelvic pain, dysmenorrhea, and infertility. Current treatments have limitations and consequently there is rising interest in effects of cannabis on pain and …
Regulatory T-cells (Tregs) are central to peripheral immune tolerance and act as key players that sustain the immune homeostasis required for embryo receptivity, implantation, and placentation. Treg dysfunction accelerates inflammation, …
In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …
Endometriosis, a chronic estrogen-dependent disease, is associated with a risk of developing gynecological cancers. The mechanisms of this association remain unclear, but emerging evidence implicates key signaling pathways, including PI3K/AKT/mTOR …