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Research progress and potential therapeutic targets of a novel disulfide stress-driven cell death-disulfidptosis in gynecological tumors and other gynecological disorders.

Disulfidptosis is a novel Nicotinamide Adenine Dinucleotide Phosphate (NADPH) deficiency-driven cell death pathway characterized by cystine overload and aberrant disulfide bond formation in actin cytoskeletal proteins, distinct from apoptosis, ferroptosis, …

Published: Oct. 25, 2025, midnight
Targeting Steroid Receptor Coactivators for the Treatment of Benign Female Reproductive Disorders.

Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …

Published: Oct. 23, 2025, midnight
How hormonal imbalances in metabolic syndrome fuel women’s cancer risk - The South First

How hormonal imbalances in metabolic syndrome fuel women’s cancer risk The South First

Published: Oct. 22, 2025, 1:30 a.m.
Addressing Meta-Inflammation in the Comprehensive Management of Chronic Pain.

Chronic pain is a widespread condition affecting millions globally, placing significant strain on healthcare systems, as evidenced by the current opioid crisis. Despite advances in pain management, conventional treatments often …

Published: Oct. 18, 2025, midnight
Women with metabolic syndrome face higher risk of gynaecological cancers, finds study - The Hindu

Women with metabolic syndrome face higher risk of gynaecological cancers, finds study The Hindu

Published: Oct. 16, 2025, 4:18 p.m.
Serum Fingerprinting-Based Integrative Dual-Omics Machine Learning for Endometriosis-Associated Ovarian Cancer.

Dual-omics, by integrating molecular information from two distinct dimensions, can offer more comprehensive perspective for complex disease. Herein, we developed an efficient functionalized mesoporous nanoparticle-coupled laser desorption/ionization mass spectrometry (fMNPLDI-MS) …

Published: Oct. 16, 2025, midnight
Association of lipid accumulation product, visceral adiposity index and endometriosis: A cross-sectional study from the 1999-2006 NHANES.

Endometriosis (EMS) is a common gynaecological disorder linked to metabolic disturbances. However, evidence on the associations between lipid accumulation product (LAP) and visceral adiposity index (VAI) with the risk of …

Published: Oct. 15, 2025, midnight
The Role of the Microbiome in Endometriosis.

Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus, leading to pain and infertility. Recent research has highlighted the important role of the …

Published: Oct. 13, 2025, midnight
Potential biomarkers for early detection of endometriosis: current state of art (what we know so far).

Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Its diagnosis remains a significant clinical challenge, often delayed by 7 to 12 …

Published: Oct. 13, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
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