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Serum Fingerprinting-Based Integrative Dual-Omics Machine Learning for Endometriosis-Associated Ovarian Cancer.

Dual-omics, by integrating molecular information from two distinct dimensions, can offer more comprehensive perspective for complex disease. Herein, we developed an efficient functionalized mesoporous nanoparticle-coupled laser desorption/ionization mass spectrometry (fMNPLDI-MS) …

Published: Oct. 16, 2025, midnight
Association of lipid accumulation product, visceral adiposity index and endometriosis: A cross-sectional study from the 1999-2006 NHANES.

Endometriosis (EMS) is a common gynaecological disorder linked to metabolic disturbances. However, evidence on the associations between lipid accumulation product (LAP) and visceral adiposity index (VAI) with the risk of …

Published: Oct. 15, 2025, midnight
The Role of the Microbiome in Endometriosis.

Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus, leading to pain and infertility. Recent research has highlighted the important role of the …

Published: Oct. 13, 2025, midnight
Potential biomarkers for early detection of endometriosis: current state of art (what we know so far).

Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Its diagnosis remains a significant clinical challenge, often delayed by 7 to 12 …

Published: Oct. 13, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
Fallopian tubes influences sperm selection and fertilization success.

This study investigates the proteomic profile of the fallopian tube following exposure to human sperm, with a focus on its role in sperm capacitation, final sperm maturation, successful fertilization, and …

Published: Oct. 6, 2025, midnight
Reproductive History and Cardio-Metabolic Risk in the Postmenopausal Age.

Menopause represents a cardio-metabolic transition, but cardiovascular (CV) health in women is highly influenced by other reproductive milestones and conditions, which delineate a cardio-reproductive lifeline. Reproductive history represents an opportunity …

Published: Sept. 30, 2025, midnight
Design and prioritization of the French surveillance program of health effects in the context of exposure to endocrine disruptors using a Delphi study.

Rapidly increasing evidence has documented that endocrine disruptors (EDs) contribute substantially to disease and disability, particularly neurodevelopmental disorders, metabolic diseases, reproductive disorders, immune and thyroid dysfunctions, as well as hormone-related …

Published: Sept. 30, 2025, midnight
From gut to gamete: how the microbiome influences fertility and preconception health.

Global fertility rates continue to decline despite advancements in assisted reproductive technologies, highlighting a significant gap in our understanding of the mechanisms underlying preconception physiology. In this commentary, we review …

Published: Sept. 26, 2025, midnight
Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility.

Endometriosis-related infertility is a prevalent reproductive health concern of global significance. Functional abnormalities of the endometrium are increasingly recognized as a pivotal contributor to infertility in affected individuals. In the …

Published: Sept. 26, 2025, midnight
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