Latest Articles

NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.

Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …

Patient- and disease-related characteristics to anticipate segmental resection for isolated rectal endometriosis: a multicenter prospective study.

To identify predictors for segmental resection in patients with an isolated rectal endometriotic nodule (i.e. involvement of at least the muscular layer in depth and up to 15cm to the …

Inflammation-Targeted Endometriosis Research Needs Pain, Mood, and Fertility-Priority Outcomes.

PGT-A Chromosomal Outcomes in Trophectoderm Biopsies from Women with Endometriosis: A Retrospective IVF Cohort Study.

Background/Objectives: Endometriosis is frequently associated with infertility and may affect several aspects of reproductive competence. However, whether women with endometriosis exhibit different preimplantation genetic testing for aneuploidy (PGT-A) outcomes compared …

Presumed Hippocampal Endometriosis Presenting as Catamenial Epilepsy: Diagnostic Challenges, MRI Follow-Up, and Comparative Review of Reported Cerebral Endometriosis Case.

Background: Cerebral endometriosis is an exceptionally rare manifestation of extrapelvic endometriosis and remains a diagnostic challenge because its clinical and imaging features may mimic more common neurological, inflammatory, vascular, or …

Endometriosis Pain: Genes linked to Inflammation Distinguish Symptomatic from Asymptomatic Disease.

Endometriosis is a multifaceted disease, causing debilitating pelvic pain in some patients, while being completely asymptomatic in others. The pathophysiology of endometriosis pain is not well understood and poorly correlated …

Impact of ethanol sclerotherapy on pelvic pain and quality of life in patients with endometriomas (ESCOMA study): protocol for a randomised clinical trial.

Endometriosis is a chronic gynecological disease associated with pelvic pain, infertility, and reduced quality of life. Ovarian endometrioma is its most common manifestation. Although laparoscopic cystectomy is widely used, concerns …

Inguinal endometriosis mimicking an inguinal hernia: A case report and literature review.

Inguinal endometriosis is a very rare extrapelvic form of endometriosis, estimated to occur in only 0.3-0.6% of women with endometriosis. It mostly affects the right round ligament running inside the …

Evaluating embryo euploidy among patients diagnosed with inflammatory bowel disease undergoing in vitro fertilization.

The impact of inflammatory bowel disease (IBD) on embryo chromosomal competence during in vitro fertilization (IVF) remains poorly defined. This study aimed to evaluate embryo euploidy rates among patients with …

Association Between Endometriosis and Autoimmune Thyroid Disease Using a Multicenter Observational Medical Outcomes Partnership (OMOP) Common Data Model.

Background: Endometriosis affects approximately 6-10% of women of reproductive age-an estimate that varies substantially with the diagnostic standard applied-and is increasingly recognized as a systemic inflammatory disease. Growing evidence implicates …