Factors released from the human placentae, including extracellular vesicles, reduce the migration of endometriotic cells: A potential therapeutic for endometriosis.
Endometriosis is characterised by the growth of abnormal endometrial tissue outside the uterus and chronic inflammation. Increasing evidence suggests that placenta extracellular vesicles (EVs) inhibit the growth and migration of …
Comparison of perioperative outcomes between laparoscopy and robotic-assisted surgery in the surgical treatment of endometriosis: a retrospective study.
Minimally invasive surgery is the gold standard for the surgical treatment of endometriosis. However, controversy remains in the literature regarding the perioperative benefits of robotic-assisted surgery compared to laparoscopic surgery, …
Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation.
Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …
A Case of Deep Infiltrating Endometriosis Undergoing Malignant Transformation to Müllerian Adenosarcoma: Case Report and Literature Review.
Müllerian adenosarcoma (MA) is a rare malignant tumor of the female reproductive system. Owing to the limited number of clinical cases and the absence of characteristic clinical manifestations, its clinical …
Simvastatin and Primaquine Identified as Potential Endometriosis Therapeutics via a Novel Epithelial-Stromal Assembloid Drug Screening Assay.
Endometriosis is an estrogen-driven, inflammatory disorder affecting ~10% of menstruators, causing severe pain. Current treatments that reduce estrogen or inflammation have inconsistent efficacy and poor tolerability. Therapies identified via drug-repositioning …