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Diagnosis and Therapy of Endometriosis. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025).

Objective The objective of this revised official guideline, published by the German Society for Gynecology and Obstetrics (DGGG) and coordinated in the joint guidelines program of the DGGG, the Austrian …

Published: Feb. 11, 2026, midnight
Barriers and Facilitators Affecting the Care of Patients with Endometriosis: A Scoping Review.

Endometriosis affects around 10-15% of women of reproductive age worldwide. Despite its prevalence and the considerable pain and psychological stress associated with the disease, the care of those affected is …

Published: Feb. 11, 2026, midnight
Obstructed Hemivagina with Ipsilateral Renal Anomaly: Radiological Diagnosis, Outcome of Surgical Management and Literature Review.

Background and Clinical Significance: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare Müllerian duct anomaly that is frequently misdiagnosed as primary dysmenorrhea, resulting in delayed intervention and …

Published: Feb. 11, 2026, midnight
Mind the gap: underreporting of key compartments in endometriosis MRI with free-text and non-disease-specific templates.

To evaluate the impact of different reporting approaches on the completeness of endometriosis documentation in pelvic MRI reports.

Published: Feb. 9, 2026, midnight
H2S-Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety.

Despite ongoing challenges in developing effective non-surgical and non-hormonal treatments for endometriosis, the psychological manifestations of the disease-particularly anxiety-remain comparatively underexplored. In this study, a hydrogen sulfide (H2S)-releasing aspirin derivative, …

Published: Feb. 8, 2026, midnight
Targeting HSP90 as a therapeutic approach for endometriosis: insights from proteomic analysis.

Endometriosis, a chronic inflammatory condition characterized by pain and infertility, remains a clinical challenge. Current hormonal and surgical treatments are often limited by side effects and high recurrence rates. In …

Published: Feb. 7, 2026, midnight
Clinical Implications of Extracellular Vesicles in Endometriosis: A Systematic Review.

Endometriosis (EM) is a chronic gynecological condition characterized by the growth of endometrial-like tissue outside the uterus. Diagnosis has traditionally been challenging due to nonspecific symptoms and reliance on invasive …

Published: Feb. 6, 2026, midnight
Safety, Pharmacokinetics, and Sex Hormone Suppression of LY01021 versus Relugolix: A Single- and Multiple-Dose Escalation Study.

LY01021 is a novel oral small-molecule gonadotropin-releasing hormone (GnRH) receptor antagonist intended for the treatment of various sex hormone-dependent disorders. This study aimed to evaluate the safety, tolerability, pharmacokinetics (PK), …

Published: Feb. 5, 2026, midnight
The role of Fusobacterium nucleatum in the pathogenesis of endometriosis: A microbial and microenvironmental perspective.

Endometriosis is a chronic, inflammatory gynecological condition characterized by the ectopic growth of endometrial-like tissue, with an unclear etiology and limited treatment efficacy. Recent studies implicate the oral and gut …

Published: Feb. 4, 2026, midnight
Nerve-sparing techniques in deeply infiltrating endometriosis: a narrative review.

Nerve-sparing gynecologic surgery has evolved as a critical advancement in the management of deeply infiltrating endometriosis, aiming to reduce postoperative dysfunction while preserving surgical efficacy. Historically, procedures such as radical …

Published: Feb. 3, 2026, midnight
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