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The long road of drug development for endometriosis - Pains, gains, and hopes.

Endometriosis, defined by the growth of endometrial tissues outside of the uterine cavity, is a global health burden for ~200 million women. Patients with endometriosis usually present with chronic pain …

Published: Oct. 18, 2024, midnight
The impact of Bisphenol-A on human reproductive health.

Bisphenol-A (BPA) is a recognized endocrine-disrupting chemical used to produce several consumer goods and products. There has been widespread exposure to BPA because of increased industrial production and use of …

Published: Oct. 18, 2024, midnight
Prevalence and Risk Factors of Endometriosis Among Infertile Women in a Tertiary Care Center in South India.

Background Endometriosis is a gynecological conundrum because of its challenging diagnosis and treatment. It seems to affect every aspect of a woman's reproductive system, rendering her incapable of conceiving or …

Published: Oct. 18, 2024, midnight
Construction and validation of a histone-related gene signature for the diagnosis of endometriosis.

Endometriosis is a common chronic disease in childbearing women and a major cause of infertility. Our study aimed to identify and validate a novel gene signature for diagnosing endometriosis based …

Published: Oct. 16, 2024, midnight
A positive ReceptivaDx result for BCL6 does not correlate with abnormal ERA results or decreased expression of receptivity-associated markers: two sides of the endometrial receptivity coin in fertility evaluation and treatment.

To investigate if a positive result on ReceptivaDx for evaluation of B-cell lymphoma 6 (BCL6), a proposed marker of progesterone resistance associated with impaired uterine receptivity, correlates with a suboptimal …

Published: Oct. 15, 2024, midnight
Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects.

Millions of children have been born throughout the world thanks to ARTs, the harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the specific effects …

Published: Oct. 14, 2024, 1:32 p.m.
Evaluating Fallopian Tube Patency: What the Radiologist Needs to Know.

Impaired tubal patency accounts for up to 35% of cases of subfertility and infertility. Hysterosalpingography (HSG) or hysterosalpingo-contrast sonography (HyCoSy) represents a first-line test in evaluating fallopian tube patency. Despite …

Published: Oct. 14, 2024, 1:29 p.m.
[Guideline for the diagnosis and treatment of endometriosis (Third edition)].

This is the third edition of guideline for the diagnosis and treatment of endometriosis in China. The second edition was published six years ago in 2015. It has been an …

Published: Oct. 14, 2024, 1:26 p.m.
Probiotics and NLRP3 mRNA inflammasome levels in women with endometriosis-related infertility undergoing assisted reproductive technologies.

This research was conducted at Bukovinian State Medical University and the Centre of Reproductive Medicine and included a total of 30 infertile women. The control group consisted of 10 women …

Published: Oct. 14, 2024, 1:24 p.m.
Robotic multiple sigmoid and rectal mucosa skinning in a multicentric deep infiltrating bowel endometriotic nodules: a case report.

Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of non-gynecological localizations represents the real surgical challenge. A 29-year-old woman underwent …

Published: Oct. 14, 2024, 1:22 p.m.
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