What is the health-related quality of life (HRQoL) at fertile and late fertile age in women with history of endometriosis?
to evaluate the association between symptoms and the site of endometriosis lesions using machine learning analysis DESIGN: retrospective study SETTING: Two tertiary hospitals.
Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by the ectopic presence of endometrial-like tissue. Although genome-wide association studies (GWAS) have identified susceptibility variants, their tissue-specific regulatory impact remains poorly …
Background: Endometriosis is a chronic inflammatory condition affecting 10-15% of women of reproductive age. Genome-wide association studies (GWASs) have accounted for only a fraction of its high heritability, indicating the …
Endometriosis is a condition that manifests through chronic pelvic pain and infertility. Current therapeutic options do not provide complete relief and may result in undesirable side effects.
Pingchong Jiangni recipe (PJR) is a Chinese herbal formula that has been used clinically for decades in the treatment of endometriosis, with effects such as shrinking the lesions and reducing …
Many women with endometriosis turn to digital sources for information. Meanwhile, large language models (LLMs) appear capable of offering health advice. This study aimed to evaluate the potential in answering …
Endometrial regeneration is a cornerstone of reproductive health, with the extracellular matrix (ECM) playing a pivotal role in tissue repair, regeneration, and fertility restoration. Dysregulated ECM remodeling is at the …
Neuropeptide S (NPS) is a potent agonist for the GPCR receptor NPSR1, implicated in various physiological and pathological processes, including inflammation. NPSR1 gene polymorphisms have been linked to asthma, inflammatory …
Endometriosis and body mass index (BMI) are known to influence reproductive outcomes, but their combined impact on in vitro fertilization (IVF) success remains uncertain.