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Growth Arrest-Specific Protein 6 Is Elevated in Endometriosis but Shows Poor Diagnostic Performance.

Growth arrest-specific protein 6 (GAS6) has an important role in regulating the immune system. Recent studies have revealed its association with the pathophysiology of endometriosis and identified GAS6 as one …

Published: Aug. 28, 2025, midnight
Large Language Models Reveal Menstruation Experiences and Needs on Social Media.

The gender knowledge gap in medicine, particularly regarding menstruation and disorders such as endometriosis, often results in delayed diagnoses and inadequate care. Many menstruating individuals report dismissal of debilitating symptoms, …

Published: Aug. 27, 2025, 12:01 a.m.
Emerging Mechanisms of NK Cell Dysfunction in Endometriosis: The Role of Autophagy, Metabolism, Cytokines, Exosomes, and Trogocytosis.

Endometriosis (EMS) is a persistent, inflammatory condition that relies on estrogen and is distinguished by the proliferation of endometrial tissue outside the confines of the uterus. The impact on the …

Published: Aug. 27, 2025, 12:01 a.m.
Correction to: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models.

Published: Aug. 27, 2025, midnight
'The Difficulty of Diagnosis Compromises Patient Care for People With Endometriosis': Interview Study With Aotearoa New Zealand General Practitioners.

General practitioners (GPs) are gatekeepers to specialist attention for endometriosis in the public system in Aotearoa New Zealand (Aotearoa-NZ). Their perspective of the endometriosis care landscape in Aotearoa-NZ has not …

Published: Aug. 27, 2025, midnight
Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation.

Endometriosis (EMs) is a common inflammatory disorder in women of reproductive age, severely impacting patients' quality of life and fertility. Current hormonal therapies offer limited efficacy, and surgical interventions often …

Published: Aug. 27, 2025, midnight
Anticlustering for sample allocation to minimize batch effects.

High-throughput sequencing enables efficient processing of DNA and RNA samples in batches, but batch effects can obscure true biological signal. We propose using anticlustering as an automated method to assign …

Published: Aug. 27, 2025, midnight
ATP/P2X4 Regulates Inflammation and Oxidative Stress in Endometriosis Through NLRP3 Inflammasome-Dependent Mechanisms.

Endometriosis (EMS) is a chronic inflammatory disorder with ectopic endometrial tissues arising in extrauterine areas. We investigated the mechanism of adenosine triphosphate (ATP)/P2X4 regulating inflammation and oxidative stress in EMS.

Published: Aug. 27, 2025, midnight
Elucidation of the mechanism of treating endometriosis with Ge Xia-Zhu Yu decoction by means of network pharmacology and molecular docking.

This study investigates the mechanism of Ge Xia-Zhu Yu decoction (GXZYT) in the treatment of endometriosis (EMS). The active components and targets of GXZYT were screened using TCMSP database and …

Published: Aug. 27, 2025, midnight
Role of Transcription Factor, LIM Homeobox 9 (LHX9) in Inflammatory Response by PGE2 and Thrombin in SERPINA1-Silencing Endometrial Stromal Cells.

Endometriosis is hypothesized to result from retrograde menstruation where cell debris including endometrial stromal cells (ESCs) travel through the fallopian tubes. This chronic inflammatory disease is characterized by inflammatory and …

Published: Aug. 27, 2025, midnight
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