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The impact of surgical intervention on time to conception and obstetric outcomes in women with endometriomas: a retrospective cohort study.

Endometriomas may adversely affect fertility; however, the necessity of its surgical management is a controversial subject. The aim of this study was to compare the time to conception, mode of …

Published: Aug. 7, 2025, midnight
Anti-cancer Drugs in Endometriosis Management: Mechanisms and Therapeutic Potential.

Endometriosis is a widespread estrogen-driven condition causing pelvic pain and infertility in women. This disease shares five features with cancer: Intrinsic growth signals, insensitivity to antiproliferative signals, impaired apoptosis, induction …

Published: Aug. 7, 2025, midnight
Extended Ovarian Transport for Centralized Tissue Cryobanking: Impact on Primordial Follicle Integrity.

To evaluate the impact of ovarian tissue transportation on human primordial follicle integrity prior to cortical tissue cryopreservation.

Published: Aug. 7, 2025, midnight
Efficacy of non-pharmacological therapies in chronic pelvic pain of endometriosis: a systematic review and meta-analysis.

Endometriosis is a condition that manifests through chronic pelvic pain and infertility. Current therapeutic options do not provide complete relief and may result in undesirable side effects.

Published: Aug. 5, 2025, midnight
Gynecologic postoperative anti-adhesion barriers: From biomaterials to barrier development.

Gynecologic postoperative adhesions (GPOA) remain an under-appreciated source of morbidity despite advances in minimally invasive surgery. Adhesions forming after myomectomy, extensive endometriosis excision, repeat caesarean section, or hysteroscopic adhesiolysis develop …

Published: Aug. 5, 2025, midnight
Endometrial regeneration and the role of the extracellular matrix: mechanisms, challenges, and future perspectives.

Endometrial regeneration is a cornerstone of reproductive health, with the extracellular matrix (ECM) playing a pivotal role in tissue repair, regeneration, and fertility restoration. Dysregulated ECM remodeling is at the …

Published: Aug. 5, 2025, midnight
Ovulatory follicular fluid promotes the clonogenicity and invasion of ectopic and eutopic endometrial cells.

Endometriosis is a chronic, estrogen-dependent disorder characterized by the ectopic growth of endometrial-like tissue. Despite its significant impact on fertility and quality of life, the pathogenesis of endometriosis remains poorly …

Published: Aug. 4, 2025, midnight
Laparoscopic ovarian drilling (LOD) versus Step-up gonadotropin therapy in infertile anovulatory PCOS women resistant to sequential letrozole and gonadotropin-based ovulation induction cycles: a randomized controlled trial.

To study the effect of laparoscopic ovarian drilling (LOD) versus step-up gonadotropin therapy on follicular response in infertile anovulatory PCOS women resistant to sequential Letrozole + HMG (Human Menopausal Gonadotropin) …

Published: Aug. 2, 2025, midnight
Insights into the Molecular Mechanisms and Signaling Pathways of Epithelial to Mesenchymal Transition (EMT) in the Pathophysiology of Endometriosis.

Endometriosis is a disease characterized by the presence of endometrial glands and stroma outside of the uterine corpus, often clinically presenting with pain and/or infertility. Ectopic lesions exhibit features characteristic …

Published: Aug. 1, 2025, midnight
Impaired Decidualization and Angiogenesis in Eutopic Endometrium of Endometriosis: Insights from In Vitro Models.

Endometriosis markedly compromises female fertility, and although endometrial dysfunction likely plays a role in this pathology, its precise mechanistic contributions remain poorly understood. This study aims to investigate the decidualization …

Published: Aug. 1, 2025, midnight
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