Orphan nuclear receptor 4A1 (NR4A1) is a member of the NR4A subfamily that was initially discovered as an intermediate early gene expressed in response to stressors, including inflammatory agents. This …
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …
Despite being one of two cardinal disease symptoms, endometriosis pain is poorly understood. Using a validated mouse model, we demonstrate that endometriosis-associated vaginal dysbiosis is sufficient to induce pain in …
Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …
Reactive oxygen species (ROS) are vital for oocyte development, yet the redox state of peritoneal fluid may differ between health and disease. This study investigates the effects of peritoneal fluid …
Menstrual blood (MB), a biofluid rich in diverse cell types and biomolecules, has emerged as a vital resource for investigating female reproductive health and diseases because of its unique composition …
Infertility has a significant impact on women, affecting them both mentally and physically. Some of the current infertility-related diseases include intrauterine adhesions, endometriosis, polycystic ovary syndrome, primary ovarian insufficiency, and …
Global Women’s Health Market to Grow at 4–5% CAGR Driven by Disease Burden and Contraceptive Demand by 2030 PharmiWeb.com
Endometriosis is a chronic inflammatory disease affecting women of reproductive age, often accompanied by chronic pelvic pain and infertility. Despite numerous studies, its pathogenesis remains incompletely understood. Increasing evidence indicates …
Endometriosis affects about 10% of women usually of reproductive age. It often has severe negative impacts on patients' quality of life, but the average time to a definitive diagnosis remains …