The Fibrinogen-to-Albumin Ratio in Endometriosis: A Step Toward Personalized Non-Invasive Diagnostics.
Background/Objectives: Endometriosis is a chronic inflammatory disease affecting up to 10-15% of women of reproductive age and is frequently associated with pelvic pain and infertility. Non-invasive biomarkers remain insufficient for …
Quantifying inflammatory resolution in human menstruation reveals disease-specific failure modes and enables a non-invasive diagnostic for endometriosis.
Inflammatory resolution is essential for tissue health, yet its dynamics remain difficult to study in humans. Menstruation is a recurrent, non-pathological inflammatory process that provides a natural window into inflammation …
Fucoxanthin regulates macrophage pyroptosis through the PI3K/AKT/mTOR signalling pathway.
Pyroptosis has been reported to occur in several diseases, such as atherosclerosis, nonalcoholic steatohepatitis, and endometriosis. Although fucoxanthin has several biological properties (particularly anti-inflammatory properties), the mechanism through which fucoxanthin …
AI-Enhanced MRI Radiomics for Discriminating Active and Fibrotic Lesions to Support Therapeutic Decision-Making in Deep Endometriosis.
This study investigates whether quantitative analysis of preoperative Magnetic Resonance Imaging (MRI) scans can differentiate deep infiltrating endometriosis (DIE) lesion types (active or fibrotic) and associate them with reported pain …
Applications of Exosomes in Female Medicine: A Systematic Review of Molecular Biology, Diagnostic and Therapeutic Perspectives.
Exosomes are nanoscale extracellular vesicles that mediate intercellular communication by transporting microRNAs, proteins, and lipids. Generated through Endosomal Sorting Complex Required for Transport (ESCRT)-dependent mechanisms or ESCRT-independent pathways, exosomes are …
Expression of concern: "Is dienogest a convenient treatment option for cesarean scar endometriosis or should it be treated surgically?". [Eur. J. Obstet. Gynecol. Reprod. Biol. 282 (2023) 110-115].