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Inhibiting NTRK2 signaling causes endometriotic lesion regression.

Endometriosis is a common gynecological disease in reproductive-age women. Although the hormone-dependent therapy is the first line treatment for endometriosis, it is not a curative regimen and associated with severe …

Published: Oct. 14, 2024, 1:21 p.m.
Risk of cancer in infertile women: analysis of US claims data.

Is female infertility associated with higher risk of cancer?

Published: Oct. 14, 2024, 1:20 p.m.
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain.

Endometriosis is a chronic, burdensome condition that is historically understudied. Consequently, there is a lack of understanding of the etiology of the disease and its associated symptoms, including infertility and …

Published: Oct. 14, 2024, 1:20 p.m.
Pelvic myofascial pain is associated with restriction of sexual activity in women with pelvic pain: a cross-sectional study.

Background Dyspareunia and restriction of sexual activity are often reported by patients with chronic pelvic pain, but less is known about which conditions or factors contribute most to these symptoms. …

Published: Oct. 13, 2024, 8:56 p.m.
The impact of war situation on endometriosis patients: Evaluating physical and mental health outcomes.

To investigate the impact of war situation on physical functioning, mental health status, and disease manifestations among endometriosis patients. Questionnaire-based study analyzing physical and psychosocial well-being. The study includes 50 …

Published: Oct. 12, 2024, midnight
RNA sequencing reveals novel molecular mechanisms of endometriosis lesion development in a mouse model.

Understanding of molecular mechanisms contributing to the pathophysiology of endometriosis, and upstream drivers of lesion formation, remains limited. Using a C57Bl/6 mouse model in which decidualized endometrial tissue is injected …

Published: Oct. 10, 2024, midnight
Surgical Technique and Fertility Outcomes: A Comprehensive Review of Open and Laparoscopic Cystectomy in Women of Reproductive Age.

Cystectomy, the surgical removal of ovarian tissue, is commonly performed in women of reproductive age to address conditions such as ovarian cysts, endometriosis, and tumors. The choice of surgical technique, …

Published: Oct. 10, 2024, midnight
Once Daily Oral Relugolix Combination Therapy Versus Placebo in Patients With Endometriosis-Associated Pain: Two Replicate Phase 3, Randomised, Double-Blind, Studies (SPIRIT 1 and 2).

The author describes the results of a study to examine the effect of three treatment regimens on pain associated with endometriosis.

Published: Oct. 9, 2024, midnight
The mixture of non-persistent endocrine-disrupting chemicals in relation to endometriosis.

Non-persistent endocrine-disrupting chemicals (EDCs) are of significant concern due to their reproductive toxicity. Previous research reported a relationship between a single type of EDCs and endometriosis. Yet, evidence regarding mixed …

Published: Oct. 9, 2024, midnight
A feasible procedure for laparoscopic cesarean scar defect repair.

In 1995, Morris first described cesarean scar defect (CSD) as an "isthmocele" by macroscopy following hysterectomy in women with a prior cesarean delivery. CSD is associated with gynecological symptoms such …

Published: Oct. 9, 2024, midnight
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