Latest Articles

Endometriosis is Widely Involved in Retroperitoneal Lymph Nodes: Rare Systemic Disseminated Manifestations.

[Pain medicine aspects of the updated S2k guideline "Diagnosis and treatment of endometriosis"].

The scheduled update of the S2k guideline "Diagnosis and treatment of endometriosis", published by the Association of the Scientific Medical Societies in Germany (AWMF; registry number 015/045), was released on …

p16 Beyond Senescence: Cancer Biology Lessons Applied to Endometriosis.

Endometriosis is an estrogen-dependent disease characterized by chronic inflammation and fibrosis and is a major cause of pelvic pain and infertility. Recent studies have reported dysregulated expression of p16INK4a, a …

Deep infiltrating endometriosis presenting as acute abdomen with extremely elevated tumor markers: a cancer-mimicking case.

Deep infiltrating endometriosis (DIE) is a rare and severe subtype of endometriosis that can cause marked distortion of pelvic anatomy. Diagnosis becomes particularly challenging when it presents as an acute …

The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.

Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …

Endometriosis-associated Pain: Mechanism, Neuroimmune Signature, and Translational Precision Strategies.

Endometriosis affects approximately 10% of reproductive-aged women worldwide and is a leading cause of chronic pelvic pain. Despite its high prevalence and substantial socioeconomic burden, the mechanisms underlying endometriosis-associated pain …

Molecular Insights Into Endometriosis for Early Detection and Therapeutic Targets.

Endometriosis is a hormone-dependent chronic inflammatory disease associated with pain and infertility, remains diagnostically and therapeutically challenging due to its multifactorial nature. Molecular mechanisms of the dynamic changes during disease …

Harnessing the murine inner cell mass mechanical environment enhances derivation of in vitro nascent primitive endoderm precursor cells.

Stem cell-based models resembling murine blastocysts represent a useful system to investigate subsequent developmental processes. While existing cell lines derived from epiblast and trophectoderm can be aggregated to form 'blastoids', …

Interpretable machine learning for endometriosis classification: a rule-based approach.

Endometriosis is a chronic gynecological disease characterized by the growth of endometrial-like tissue outside the uterus, leading to pelvic pain, infertility, and other major health complications. Though some studies have …

Giant Cesarean Section Scar Endometriosis Presenting with Cyclic Pain: A Neglected Clinical Manifestation-A Case Report.

Endometriosis is a chronic gynecological disorder characterized by the presence of endometrium-like tissue outside the uterine cavity. It is most commonly found in the pelvic organs but may also occur …