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ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Yearning for movement. A qualitative interview study exploring physical activity in the context of endometriosis-associated chronic pain.

BackgroundChronic pain is a common symptom of endometriosis with significant negative impact on physical and social activities. Patients perceive that healthcare professionals lack knowledge about the condition, and that available …

Published: May 21, 2026, midnight
Developmental Versus Chromosomal Competence in Endometriosis: A Stepwise IVF Outcome Analysis.

Background and Objectives: Endometriosis is a multifactorial gynecological condition associated with impaired fertility; however, its impact on embryo competence remains incompletely understood. This study aimed to evaluate embryo competence through …

Published: May 21, 2026, midnight
Is Recurrent Endometriosis a Reprogrammed Disease? Molecular Persistence Beyond Surgical Clearance.

Background: Endometriosis is traditionally conceptualized as a localized gynecological disorder characterized by the presence of ectopic endometrial tissue. However, high recurrence rates following apparently complete surgical excision challenge this lesion-based …

Published: May 21, 2026, midnight
Endometriosis and adverse pregnancy outcomes in primiparous women: a retrospective cohort study.

To assess whether pre-existing endometriosis is associated with specific adverse pregnancy and delivery outcomes in primiparous women.

Published: May 20, 2026, midnight
Patient characteristics and lifestyle determinants of quality of life among women with endometriosis: a systematic review.

Endometriosis is a chronic inflammatory disease presenting with debilitating symptoms strongly impacting patients' quality of life (QoL). Assessing QoL is crucial for understanding the full patient experience beyond clinical symptoms. …

Published: May 20, 2026, midnight
Ethics of non-oncological fertility preservation from the perspective of the four principles of bioethics.

Fertility preservation refers to the cryopreservation of gametes, embryos, or gonadal tissue before age, disease, or medical treatment affects reproductive capacity. Fertility preservation techniques were originally developed for cancer patients. …

Published: May 20, 2026, midnight
Pelvic Müllerian duct cyst with coexisting endometriosis: a case report.

Müllerian duct cyst (MDC) is an uncommon congenital lesion arising from incomplete regression of the paramesonephric duct. It typically presents as a midline pelvic cystic lesion and is often asymptomatic, …

Published: May 19, 2026, midnight
ESPriT1: The effectiveness of laparoscopic treatment of isolated superficial peritoneal endometriosis for managing chronic pelvic pain in women: a randomised controlled feasibility trial.

Endometriosis is a chronic pain condition that affects >190 million people worldwide. It is recommended in clinical guidelines to remove the most common type of endometriosis, 'superficial peritoneal endometriosis' (SPE), …

Published: May 19, 2026, midnight
Piezo1 mediates hypoxia-induced endometriosis fibrosis via the mtDNA -dependent cGAS-STING pathway.

Endometriosis (EMs) is a prevalent gynecological disorder characterized by the ectopic growth of functional endometrial tissue, and its fibrotic pathology represents a primary contributor to chronic pain and infertility in …

Published: May 19, 2026, midnight
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