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Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis.

Endometriosis is a benign yet invasive disease characterized by ectopic endometrial growth and immune remodeling. While emerging evidence implicates cellular senescence in disease progression, the underlying mechanisms remain largely undefined. …

Published: March 28, 2026, midnight
Demographic and hematological differences between endometriosis and menorrhagia in Saudi women: A retrospective observational study of 946 patients.

Endometriosis and menorrhagia are prevalent gynecological conditions with overlapping symptoms, yet comparative data from Middle Eastern populations remain scarce. We aimed to comprehensively characterize demographic and hematological differences between these …

Published: March 28, 2026, midnight
Revealing the immune landscape of menstrual blood: unlocking insights into activation, exhaustion, and mitochondrial mass for reproductive health.

Reproductive disorders such as endometriosis and polycystic ovary syndrome (PCOS) are increasingly recognized as immune-mediated conditions, yet their immunopathology remains poorly understood. Menstrual blood, a noninvasive and biologically relevant sample, …

Published: March 27, 2026, midnight
Contraceptive-Induced Weight Gain-Myth and Reality Review.

The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane …

Published: March 27, 2026, midnight
Charting the nerve-immune axis in endometriosis.

Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant sensory …

Published: March 26, 2026, midnight
Reduced GEN1 Expression Is Associated with Elevated DNA Damage and Impaired Proliferation in Endometriosis-Derived Endometrial Organoids.

Endometriosis affects approximately 10% of reproductive-age women and is associated with genomic instability; however, the contribution of specific DNA repair deficiencies remains poorly understood. This study investigated the expression and …

Published: March 26, 2026, midnight
‘There is hope’ for endometriosis patients: World Endometriosis Day to be honored locally this Saturday - TheUnion.com

‘There is hope’ for endometriosis patients: World Endometriosis Day to be honored locally this Saturday TheUnion.com

Published: March 25, 2026, 9:45 a.m.
A heterogeneous graph neural network for candidate gene prediction in endometriosis.

Precision medicine applications depend on elucidating the underlying molecular mechanisms of disease. However, many disorders, such as endometriosis, remain poorly characterised genetically due to data scarcity, positive-unlabelled (PU) imbalance, and …

Published: March 23, 2026, midnight
Woman Left Medically Infertile After Seven Surgeries For Endometriosis That She Did Not Have - Health and Me

Woman Left Medically Infertile After Seven Surgeries For Endometriosis That She Did Not Have Health and Me

Published: March 20, 2026, 4:04 a.m.
The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency.

The LYSET gene encodes the LYSET transmembrane protein, which regulates lysosome biogenesis by activating the mannose-6-phosphate (M6P) pathway. This is an autosomal recessive, ultrarare, and severe progressive skeletal dysplasia with …

Published: March 20, 2026, midnight
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