Repurposing ramipril to mitigate EMT-like transition in endometriosis by PI3K/AKT/S6K1 signalling pathway: a study in endometriosis induced rats.
Endometriosis, an atypical benign disorder, may disrupt epithelial-mesenchymal transition (EMT) due to a dysregulated balance between matrix metalloproteinases (MMPs) and their inhibitors. Ramipril, an angiotensin converting enzyme (ACE) inhibitor, is …
Different types of abdominal wall endometriosis have different clinical features and surgical outcomes.
To compare the differences in clinical characteristics between different types of abdominal wall endometriosis (AWE) according to the invasive levels of tissue mass.
Transvaginal ultrasound for deep endometriosis: Prospective validation of SRU criteria and diagnostic value of indirect signs.
The SRU consensus on pelvic ultrasound proposed standardized augmented ultrasound, but its validity and indirect signs' role require validation. This study will explore the application value of this consensus in …
Clinical and cost-effectiveness of medical management versus surgery for deep infiltrating endometriosis: synopsis from the DIAMOND RCT.
Deep endometriosis causes significant pain which adversely affects quality of life and utilises healthcare and wider societal resources. Laparoscopic excision of endometriosis has shown to improve pain symptoms in observational …
Maternal endometriosis: An independent risk factor for long-term infectious morbidity of the offspring.
Endometriosis, a debilitating disease characterized by chronic inflammation, might be associated with adverse pregnancy outcomes. However, the long-term health implications for offspring born to mothers with endometriosis remain inadequately explored. …
Developing a Trauma-Informed Social Media Campaign to Disseminate Endometriosis-Specific Qualitative Art-Based Research Findings: Tutorial.
Trauma-informed approaches can promote the creation of systems that prioritize safety and empowerment to improve patient well-being. These approaches are especially important in sexual and reproductive health care, where patients …
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma.
Ovarian clear cell carcinoma (CCC) is an aggressive subtype of ovarian cancer that is resistant to conventional chemotherapy, resulting in poor prognosis. CCC develops from endometriosis, which exposes tumor cells …