Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association …
Patient-reported outcome measures (PROMs) capture patients' experiences and perspectives of symptoms. One approach involves measuring the "most bothersome symptom," an outcome recommended in some regulatory guidance and core outcome sets. …
The meiotic spindle is essential for accurate chromosome segregation during oocyte maturation and fertilization, and its alteration might be considered a major contributor to age-related aneuploidy and reproductive failure. Spindle …
Endometriosis is a chronic inflammatory disease characterized by substantial heterogeneity in pain, lesion behavior, and treatment response. Although hormonal and surgical therapies can reduce disease activity and symptoms, their effects …
Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …
Endometriosis is a chronic, estrogen-dependent inflammatory disease that, despite its benign histology, displays several cancer-relevant features, including clonal expansion, somatic alteration-associated lesion evolution, tissue invasion, apoptosis resistance, immune evasion, angiogenesis, …
Endometriosis is a chronic inflammatory disorder affecting 5-10% of women of reproductive age and is associated with chronic pain and infertility. While research has mainly focused on local lesions, systemic …
Fibroblast activation protein (FAP) is expressed in the fibroinflammatory stroma of endometriosis, but its relationship to conventional imaging visibility is unknown. We evaluated FAP expression in deep endometriosis (DE) and …
The relationship between endometriosis and cardiovascular disease (CVD) risk remains unclear. This study aimed to evaluate the association between endometriosis and CVD risk, to examine whether the association was affected …