Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …
Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …
Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …
In vitro fertilization (IVF) has revolutionized assisted reproductive technologies (ART), profoundly transforming infertility treatment since its inception. This procedure involves fertilizing an egg with sperm in a controlled laboratory environment, …
Endometriosis increases ovarian cancer (OC) risk through genetic mutations, chronic inflammation, and hormonal dysregulation, yet the underlying molecular pathways remain underexplored. This study aims to identify endometriosis-associated prognostic biomarkers in …
Evidence have indicated a correlation between sleep disorders and endometriosis, but the causal relationship remains uncertain. This study utilized Mendelian randomization (MR) approach to investigate the causal associations between sleep …
Endometriosis is a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, with emerging evidence highlighting a significant genetic contribution to its etiology. While genome-wide association studies have …
Genetic variation associated with side effects of hormonal contraception exposure: A narrative review Frontiers
COMMENTARY: Early cancer detection, with new tools and genetic testing, saves lives Jefferson City News Tribune
Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …