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Impaired Decidualization and Angiogenesis in Eutopic Endometrium of Endometriosis: Insights from In Vitro Models.

Endometriosis markedly compromises female fertility, and although endometrial dysfunction likely plays a role in this pathology, its precise mechanistic contributions remain poorly understood. This study aims to investigate the decidualization …

Published: Aug. 1, 2025, midnight
Activated eosinophil plays a role in promoting fibrosis in endometriotic lesion.

The fibrosis mechanism in endometriosis is not elucidated. We investigated the role of eosinophil in fibrosis of endometriosis. The endometriotic stromal cells (ESCs) and endometrial epithelial cells (EECs) were subjected …

Published: July 31, 2025, midnight
Membrane Progesterone Receptor Beta Regulates the Decidualization of Endometrial Stromal Cells in Women with Endometriosis.

Endometriosis is a disorder characterized by the presence of endometrial tissue outside the uterus, leading to dyspareunia, chronic pelvic pain, dysuria, and infertility. The latter has been related to implantation …

Published: July 28, 2025, midnight
Sulforaphane Alleviates PACS 2-Mediated Oxidative Stress Damage in Porcine Endometrial Stromal Cells Induced by Zearalenone - ACS Publications

Sulforaphane Alleviates PACS 2-Mediated Oxidative Stress Damage in Porcine Endometrial Stromal Cells Induced by Zearalenone ACS Publications

Published: July 25, 2025, 1:42 a.m.
Analysis of Vitamin D and VDR Expression in Women with Advanced Endometriosis: A Case-Control Study in Thailand.

Background: Vitamin D has anti-inflammatory and immunomodulatory properties that may influence the pathophysiology of endometriosis. This study investigated the association between vitamin D levels and endometriosis, and vitamin D receptor …

Published: June 30, 2025, midnight
Upregulation of miR-183 inhibits the invasion and migration of endometrial stromal cells in endometriosis patients by downregulating Ezrin - Frontiers

Upregulation of miR-183 inhibits the invasion and migration of endometrial stromal cells in endometriosis patients by downregulating Ezrin Frontiers

Published: June 3, 2025, 6:52 p.m.
Intra-ovarian injection of autologous menstrual blood-derived-mesenchymal stromal cells: a safe and promising method to improve pregnancy rate in poor ovarian responders.

Poor ovarian response (POR) significantly reduces the success rates of fertility treatments. This study investigates the long-term efficacy and potential complications associated with autologous menstrual blood-derived mesenchymal stromal cells (MenSCs) …

Published: April 12, 2025, midnight
In vitro effects of ABT-263, a BH3 mimetic, on fibrotic phenotype in endometriotic and endometrial stromal cells.

A recent study has shown that myofibroblasts are primed for apoptosis when survival pathways are inhibited under fibrosis. This knowledge of apoptosis priming led to the development of methods to …

Published: April 10, 2025, midnight
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.

Endometriosis is marked by the ectopic growth, spread, and invasion of endometrial tissue beyond the uterus, resulting in recurrent bleeding, pain, reproductive challenges, and the formation of nodules or masses. …

Published: April 1, 2025, midnight
Immunopathology of Endometriosis, Molecular Approaches.

Endometriosis (EMS) is a common chronic gynecological disorder affecting 5%-10% of reproductive-age women, often causing infertility, dyspareunia, pain, and limitations in physical and sexual activities. This condition is defined by …

Published: March 26, 2025, midnight
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