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High-concentration estradiol promotes platelet activation and thrombosis through Src-ADP axis.

Pregnant women, as well as patients with endometriosis and some ovarian tumors, may experience a state of high estrogen levels. However, the role of high estrogen in platelet function and …

Published: June 3, 2026, midnight
Executive Functions Mediate Between Endometriosis Burden and Women's Daily Life.

To examine (1) group differences in executive functioning, disease burden, occupational balance and quality of life between women with endometriosis and healthy controls; (2) associations between pain-related and psychological disease …

Published: June 3, 2026, midnight
UCA1 facilitates endometriosis progression through EIF4A3-mediated stabilization of E2F1 mRNA and enhanced glycolysis.

Long non-coding RNA Urothelial carcinoma-associated 1 (UCA1) is a pivotal regulator in the progression of endometriosis (EMs), yet its mechanistic role remains elusive. This study identified UCA1 as a factor …

Published: June 2, 2026, midnight
Analysis of adverse events following COVID-19 vaccination and infection: A retrospective, comparative cohort study using a claims database from Discovery Health, a managed care organisation in South Africa.

Adverse events following COVID-19 vaccination have been studied extensively in recent years. However, there remains a paucity of data directly comparing adverse events among COVID-19 vaccinees and individuals with SARS-CoV-2 …

Published: June 2, 2026, midnight
Endometriosis-Associated Infertility: A Review of Pathophysiological Mechanisms and Current Treatment Strategies.

Background: Endometriosis affects 10-15% of reproductive-aged women and is a leading cause of infertility through anatomical, inflammatory, and molecular mechanisms. Objective: This review synthesizes current evidence on the pathophysiology of …

Published: June 2, 2026, midnight
Surgical Treatment Experience of Intestinal Endometriosis.

Retrospective descriptive cohort.

Published: June 1, 2026, midnight
Underpowered study design invalidates conclusions of LTAP versus LWI in peritoneal endometriosis surgery.

Published: May 30, 2026, midnight
Navigating undone science: The search for adequate endometriosis care.

Endometriosis is an estrogen-dependent disease in which tissue similar to the lining of the uterus grows elsewhere in the body leading to a variety of symptoms including heavy and prolonged …

Published: May 30, 2026, midnight
Safety evaluation of a novel progesterone vaginal ring (PVR) for luteal phase support: SARA trial.

After manufacturing changes, the safety and tolerability of the progesterone vaginal ring (PVR) was compared to findings from the similarly designed phase 3 trial. This prospective, open-label, single-arm, multi-center U.S. …

Published: May 29, 2026, midnight
Central sensitization in patients with chronic pelvic pain resistant to hormonal therapy: A cross-sectional study of prevalence and clinical correlates in a tertiary referral cohort.

Chronic pelvic pain (CPP) affects over 25% of women, with endometriosis being a predominant cause. Central sensitization, particularly pelvic and perineal pain central sensitization (PPCS), is increasingly recognized as a …

Published: May 28, 2026, midnight
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