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Thyroid autoimmunity, thyroid function, and endometriosis: reproductive immune-endocrine crosstalk and causal uncertainty.

Endometriosis is an estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, repeated treatment, and impaired quality of life. Thyroid dysfunction and thyroid autoimmunity are also common in reproductive-aged women and …

Published: Aug. 7, 2026, midnight
Endometriosis subtypes and risk of type 2 diabetes: the Advancing Research on Cardiovascular Health and Endometriosis Study (ARCHES) retrospective cohort study.

Endometriosis is a heterogeneous inflammatory condition that may influence long-term metabolic health. Prior studies have reported largely null associations with type 2 diabetes, potentially missing subtype-specific and subgroup heterogeneity. We …

Published: Aug. 6, 2026, midnight
Association of Autoimmune Hyperthyroidism and Endometriosis, With an Endometrioma Rupture as a Complication: A Case Report and Review of the Literature.

This case report examines the association between autoimmune thyroid disease, more commonly known as Graves' disease, and endometriosis with a focus on the complication of an endometrioma rupture. The interplay …

Published: Aug. 5, 2026, midnight
Autoimmune hypothyroidism and endometriosis: evidence from bidirectional Mendelian randomization and an independent clinical cohort analysis.

Observational studies have reported comorbidity between autoimmune thyroid disease and endometriosis, but whether this reflects a direct causal relationship or shared susceptibility remains unclear. We evaluated the bidirectional relationship between …

Published: Aug. 4, 2026, midnight
Investigation of the miRNA27a rs895819, miRNA222 rs2858060 and miRNA499a rs3746444 polymorphisms in Endometriosis.

The present study aimed to determine the allelic and genotypic frequencies of the miRNA27a rs895819, miRNA222 rs2858060 and miRNA499 rs3746444 polymorphisms and their possible association with endometriosis. This case-control study …

Published: Aug. 3, 2026, midnight
Fertility Treatments and the Risk of Kawasaki Disease Among Offspring.

Kawasaki disease is a leading cause of acquired heart disease among children in high-income countries, but potential associations between fertility treatments and Kawasaki disease remain unknown, despite both becoming increasingly …

Published: Aug. 3, 2026, midnight
Dietary and Environmental Exposure to Toxic Elements in Endometriosis: A Missing Piece of the Etiological Puzzle?

Background/Objectives: Endometriosis is a chronic estrogen-dependent disease with a complex and incompletely understood etiology. Environmental exposure to toxic elements, including cadmium, lead, mercury, and arsenic, may contribute to its development …

Published: Aug. 2, 2026, midnight
Expression Profiling of Immune-Related Genes in Different Samples from Patients with Endometriosis Revealed Upregulation of THBS1, CHGB and CYR61.

Endometriosis is a chronic, inflammatory, estrogen-dependent disease that affects approximately 6-10% of women of reproductive age. The present study aimed to investigate the expression of 48 immune-related genes in different …

Published: Aug. 1, 2026, midnight
Shared Genetic Architecture and Pleiotropic Loci Linking Endometriosis and Inflammatory Bowel Disease: An Integrative GWAS, Colocalization, and Mendelian Randomization Study.

Endometriosis (EMS) and inflammatory bowel disease (IBD) are both chronic inflammatory disorders with overlapping clinical features, suggesting a potentially shared etiology. Although epidemiological studies have reported an association between the …

Published: July 29, 2026, midnight
Association of immune-inflammatory indices with focal adenomyosis of the outer myometrium in deep infiltrating endometriosis.

Deep infiltrating endometriosis (DIE) and focal adenomyosis of the outer myometrium (FAOM) are closely related chronic inflammatory conditions that often coexist. The systemic immune-inflammation index (SII), systemic inflammation response index …

Published: July 29, 2026, midnight
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