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Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review.

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …

Published: July 16, 2025, midnight
Co-Occurrence of Endometriosis with Systemic Lupus Erythematosus: Genetic Aspects.

Previous studies have shown that patients with a history of endometriosis have an increased susceptibility for developing a big number of comorbidities, including various autoimmune diseases. Endometriosis is a complex, …

Published: July 16, 2025, midnight
Prolonged oral GnRH-antagonist administration before euploid embryo transfer in patients with endometriosis: a prospective randomized pilot non-inferiority trial.

Is oral administration of a gonadotrophin releasing hormone (GnRH) antagonist for 2 months before euploid embryo transfer in patients with endometriosis non-inferior to intramuscular administration of a long-acting GnRH agonist …

Published: July 11, 2025, midnight
Functions of RhoA in the female reproductive system.

The Ras homolog gene family member A (RhoA) is a small GTPase. RhoA plays major roles in cytoskeletal regulation, transcriptional control, and cell cycle maintenance. RhoA is widely expressed in …

Published: May 15, 2025, midnight
Recent advancements and future applications of intrauterine drug delivery systems.

Intrauterine devices (IUDs) are drug-device combination products that are placed inside the uterus above the endometrium. IUDs contain a therapeutic agent used for contraception and have been shown to have …

Published: April 7, 2025, midnight
Role of miRNA polymorphisms on male and female infertility and recurrent implantation failure.

MiRNAs regulate gene expression, impacting reproductive health, such as infertility and implantation failure. This study investigated the association between miRNA polymorphisms and male infertility (azoospermia, oligospermia), female infertility (endometriosis), and …

Published: April 4, 2025, midnight
Artificial intelligence applications in endometriosis imaging.

Artificial intelligence (AI) may have the potential to improve existing diagnostic challenges in endometriosis imaging. To better direct future research, this descriptive review summarizes the general landscape of AI applications …

Published: April 1, 2025, midnight
The Effects of Endometriosis on Oocyte and Embryo Quality.

Endometriosis is a complex and multifaceted gynecological disorder characterized by the abnormal growth and presence of endometrial-like tissue outside the confines of the uterine cavity. It can lead to a …

Published: March 28, 2025, midnight
Immunopathology of Endometriosis, Molecular Approaches.

Endometriosis (EMS) is a common chronic gynecological disorder affecting 5%-10% of reproductive-age women, often causing infertility, dyspareunia, pain, and limitations in physical and sexual activities. This condition is defined by …

Published: March 26, 2025, midnight
Risk factors for recurrent implantation failure as defined by the European Society for Human Reproduction and Embryology.

What are the unrecognized risk factors for recurrent implantation failure (RIF) as defined in the ESHRE recommendation?

Published: March 26, 2025, midnight
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