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Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.

Endometriosis (EM) is a widely recognized disorder in gynecological endocrinology. Although hormonal therapies are frequently employed for EM, their side effects and outcome limitations underscore the need to explore the …

Published: Jan. 22, 2025, midnight
Causal analysis of dietary preferences and the risk of endometriosis using large-scale population data.

Dietary factors have recently been recognized as potentially influential in the pathogenesis of endometriosis (EM), yet studies on the causal relationship between dietary preferences and EM are limited. The present …

Published: Jan. 21, 2025, midnight
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses - Nature.com

Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses Nature.com

Published: Jan. 19, 2025, 3:56 p.m.
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses.

This study aimed to assess the causal relationship between lipidome and female reproductive diseases (FRDs) using an advanced series of Mendelian randomization (MR) methods. This study utilized genome-wide association study …

Published: Jan. 19, 2025, midnight
Causal effects of genetically determined circulating metabolites on endometriosis: A Mendelian randomization study.

Endometriosis (EMs) is a common gynecological disease accompanied by metabolic disturbances. However, the causality between metabolites and the risk of EMs remains unclear. We conducted a 2-sample Mendelian randomization (MR) …

Published: Jan. 16, 2025, midnight
Association between triglyceride-glucose index and endometriosis: Results from a cross-sectional study and Mendelian Randomization study - «Кавказ Пост» - новости Северного Кавказа и Закавказья

Association between triglyceride-glucose index and endometriosis: Results from a cross-sectional study and Mendelian Randomization study «Кавказ Пост» - новости Северного Кавказа и Закавказья

Published: Jan. 12, 2025, 11:03 p.m.
Association between triglyceride-glucose index and endometriosis: results from a cross-sectional study and Mendelian randomization study - Frontiers

Association between triglyceride-glucose index and endometriosis: results from a cross-sectional study and Mendelian randomization study Frontiers

Published: Jan. 9, 2025, 8:23 p.m.
Association between triglyceride-glucose index and endometriosis: results from a cross-sectional study and Mendelian randomization study.

Triglyceride-glucose (TyG) index has been found to be associated with female reproductive disorders, but its relationship with the risk of endometriosis is unknown. Therefore, the aim of this study was …

Published: Jan. 9, 2025, midnight
The Evidence-Based Medicine Management of Endometriosis Should Be Updated for the Limitations of Trial Evidence, the Multivariability of Decisions, Collective Experience, Heuristics, and Bayesian Thinking.

Background/Objectives: The diagnosis and treatment of endometriosis should be based on the best available evidence. Emphasising the risk of bias, the pyramid of evidence has the double-blind, randomised controlled trial …

Published: Jan. 3, 2025, midnight
Identification of potential druggable targets for endometriosis through Mendelian randomization analysis - Frontiers

Identification of potential druggable targets for endometriosis through Mendelian randomization analysis Frontiers

Published: Dec. 31, 2024, 10:02 a.m.
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