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The interplay of microbiome, molecular mechanisms, and fertility -an integrated review.

The human microbiome, particularly the gut and reproductive tract microbiota, plays a critical role in regulating fertility through complex molecular and immunological mechanisms. This review synthesizes emerging evidence on the …

Published: Dec. 26, 2025, midnight
In Situ Characterization and Deep Profiling of Engineered Multispecific Nanoparticle Metabolite Coronas for Precise Serum Diagnostics.

Upon exposure to biofluids, engineered nanoparticles (NPs) spontaneously form reproducible biomolecular coronas via selective diverse biomolecule adsorption. The corona characterization of metabolites poses greater analytical challenges than proteins due to …

Published: Dec. 26, 2025, midnight
The Significance of Serum CA-125 Level on the Live Birth Rates of In Vitro Fertilisation in Women with Endometriosis.

Background and Objectives: To evaluate the significance of serum CA-125 level on the live birth rate of in vitro fertilization (IVF) in women with endometriosis. Materials and Methods: This retrospective …

Published: Dec. 26, 2025, midnight
Vitamin D in Endocrine Disorders: A Broad Overview of Evidence in Musculoskeletal, Thyroid, Parathyroid, and Reproductive Disorders.

Vitamin D is well established for its skeletal effects, being a cornerstone of several endocrine disorders. In recent years, it has come under investigation as a potential disease-modifying drug in …

Published: Dec. 26, 2025, midnight
Identification and Subtype Analysis of Lipid Metabolism-Related Diagnostic Biomarkers for Endometriosis Based on WGCNA and Machine Learning.

Endometriosis (EM), a disorder driven by persistent systemic inflammation, impacts around 10% of women in their reproductive period, often diagnosed only via surgery. Metabolic alterations, particularly in lipid metabolism, may …

Published: Dec. 24, 2025, midnight
Molecular and Immune Microenvironmental Changes Across Endometrial Lesions: A Comprehensive Immunohistochemical and Clinical Analysis of Progression From Benignity to Carcinoma.

Adenomyosis and endometriosis are estrogen-driven disorders with a recognized potential for malignant transformation, particularly through atypical endometriosis. The molecular and immune mechanisms underlying this progression remain incompletely understood. However, clinical …

Published: Dec. 24, 2025, midnight
Effectiveness of an anti-inflammatory diet before in vitro fertilisation in women with endometriosis: protocol for a randomised controlled trial.

Endometriosis is a common, benign, chronic inflammatory disease with multiple consequences, from chronic pain to systemic comorbidities and poor quality of life. As it usually affects people of reproductive age, …

Published: Dec. 23, 2025, midnight
Correction: Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis.

[This corrects the article DOI: 10.3389/fimmu.2023.1115504.].

Published: Dec. 23, 2025, midnight
Endometriosis: From Genes to Global Burden.

Endometriosis has a significant impact on the social, psychological, psychosomatic, and physical aspects of women's lives. There is increasing evidence that endometriosis has to be seen as a systemic and …

Published: Dec. 23, 2025, midnight
Fertility preservation in endometriosis: current strategies and outcomes.

Endometriosis is a frequent chronic estrogen-dependent condition that can significantly impair fertility and reduce the quality of life in affected individuals. Women with endometriosis face a 30-50% risk of infertility. …

Published: Dec. 22, 2025, midnight
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