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Identification and Validation of Novel Combinatorial Genetic Risk Factors for Endometriosis across Multiple UK and US Patient Cohorts.

Endometriosis affects about 10% of women usually of reproductive age. It often has severe negative impacts on patients' quality of life, but the average time to a definitive diagnosis remains …

Published: Aug. 15, 2025, midnight
Detection of bacterial vaginosis-associated bacteria and outcomes during clinical gynaecological conditions using qPCR: A retrospective cohort study.

Endometriosis, chronic endometritis (CE), unexplained infertility (UI), and recurrent pregnancy loss (RPL) are gynecological conditions frequently associated with inflammation and alterations in the endometrial microbiome. The presence of bacterial vaginosis-associated …

Published: Aug. 15, 2025, midnight
AARS1 promotes endometriosis progression by promoting the lactylation of Snail1.

The widely accepted theory of endometriosis posits that endometriosis stems from the translocation of endometrial tissue through the fallopian tubes into the abdominal cavity. However, the exact pathogenesis and critical …

Published: Aug. 15, 2025, midnight
Hepatic Endometriosis Misdiagnosed as Hepatic Epithelioid Hemangioendothelioma.

We describe the case of a young 42-year-old female who suffered from cyclical right upper quadrant abdominal pain that led to an emergency department visit where an intrahepatic mass was …

Published: Aug. 15, 2025, midnight
Endometriosis and chronic pelvic pain management: Between a rock (denial) and a hard place (overdiagnosis).

Published: Aug. 14, 2025, midnight
Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases.

The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …

Published: Aug. 14, 2025, midnight
Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis Patients.

Endometriosis is a chronic, estrogen-dependent condition affecting over 190 million women globally, characterized by the ectopic presence of endometrial-like tissue that leads to inflammation, pain, and infertility. Despite its prevalence, …

Published: Aug. 14, 2025, midnight
Impact of a National Public Health Plan on the time frame for moderate and severe endometriosis diagnosis.

to study the time from symptom onset to the diagnosis of moderate and severe endometriosis and to compare this delay before and after the implementation of a National Endometriosis Public …

Published: Aug. 14, 2025, midnight
Polypoidal rectal endometriosis-a diagnostic dilemma.

Polypoidal rectal endometriosis is a rare and diagnostically challenging manifestation of deep infiltrating endometriosis that may mimic colorectal malignancy, especially in women lacking classical cyclical symptoms. We report such a …

Published: Aug. 13, 2025, midnight
AntiCD44 antibody-conjugated gold nanoparticles for targeted photothermal therapy of endometriotic cells.

Endometriosis is a chronic gynecologic disease that needs newer and safer treatments. The proposed work aims to develop a nanosystem based on gold nanoparticles (AuNPs) to actively target human endometriosis …

Published: Aug. 13, 2025, midnight
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