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Mitochondrial dynamics: molecular mechanism and implications in endometriosis.

Endometriosis affects about 10% of women of reproductive age, leading to a disabling gynecologic condition. Chronic pain, inflammation, and oxidative stress have been identified as the molecular pathways involved in …

Published: Jan. 28, 2025, midnight
Weighing up GnRH agonist therapy for endometriosis: outcomes and the treatment paradigm.

Endometriosis is a chronic inflammatory estrogen-dependent disease affecting 10% of women worldwide leading to chronic pelvic pain and infertility which may be treated clinically or surgically.

Published: Jan. 25, 2025, midnight
Pathogenesis, Diagnosis, and Management of Inguinal Endometriosis: A Case Series of Six Patients.

Inguinal endometriosis is a less common form of endometriosis. Therefore, there is no consensus regarding its pathogenesis or treatment. In this study, we retrospectively reviewed the pathogenesis and treatment of …

Published: Jan. 24, 2025, midnight
Multiple lesion inductions intensify central sensitization driven by neuroinflammation in a mouse model of endometriosis.

Endometriosis is an inflammatory disease associated with chronic pelvic pain (CPP). Growing evidence indicates that endometriotic lesions are not the sole source of pain. Instead, central nervous system (CNS) dysfunction …

Published: Jan. 24, 2025, midnight
Clinical effectiveness of progestogens compared to combined oral contraceptive pills in the treatment of endometriosis: A systematic review and meta-analysis.

Endometriosis involves the growth of endometrium-like cells outside the uterus, affecting reproductive-aged women. Symptoms such as dysmenorrhea, pelvic pain, and infertility significantly impair quality of life. Among therapeutic options, progestogens …

Published: Jan. 23, 2025, midnight
Moving beyond pain: the relationship between physical activity and physical self-concept among young women with endometriosis.

Endometriosis is a painful non-curable disease that affects women's quality of life, reducing their self-esteem and consequently their mental well-being. However, enhancing the physical self-concept could induce the development of …

Published: Jan. 23, 2025, midnight
Appendiceal Intussusception: A Rare Diagnosis and the Role of Imaging in Its Detection.

Appendiceal intussusception is a rare condition characterized by the invagination of the appendix into the base of the cecum. In some cases, this condition can lead to obstruction, ischemia, and …

Published: Jan. 23, 2025, midnight
Management of Common Benign Gynecologic Diseases in Postmenopausal Women.

This study investigated the impact of menopause on the progression and management of common benign gynecological conditions such as polycystic ovary syndrome, endometriosis, uterine fibroids, and adenomyosis. These conditions often …

Published: Jan. 22, 2025, midnight
Identification of hub biomarkers and immune cell infiltrations participating in the pathogenesis of endometriosis.

Endometriosis (EM) is a chronic disease that can cause pain and infertility in patients. As is well known, immune cell infiltrations (ICIs) play important roles in the pathogenesis of EM. …

Published: Jan. 22, 2025, midnight
Female chronic pelvic pain: From trauma-informed assessment to evidence-based treatment.

Female chronic pelvic pain (CPP) is a common, complex, multifactorial disorder that can negatively affect sexual functioning and emotional well-being. Effective assessment necessitates a comprehensive patient history and trauma-informed physical …

Published: Jan. 22, 2025, midnight
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