C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis.
Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic …
Artificial intelligence-driven decision tree model for predicting quality of life determinants in women with endometriosis.
Endometriosis significantly impacts the quality of life (QoL) of affected women due to its complex symptomatology. This study aimed to develop a decision tree-based model to identify the key determinants …
Anti-cancer Drugs in Endometriosis Management: Mechanisms and Therapeutic Potential.
Endometriosis is a widespread estrogen-driven condition causing pelvic pain and infertility in women. This disease shares five features with cancer: Intrinsic growth signals, insensitivity to antiproliferative signals, impaired apoptosis, induction …