Endometriosis is a chronic inflammatory condition characterized by the presence of endometrial tissue outside the uterus, leading to pelvic pain and infertility. It affects approximately 10% of women of reproductive …
To evaluate the feasibility, interobserver reproducibility, reporting efficiency, and perceived clinical impact of the Deep Pelvic Endometriosis Index (dPEI) when implemented as part of structured MRI reporting in routine clinical …
Investigating the genetic influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on key inflammatory biomarkers-Interleukin-1β, Interleukin-6, and high-sensitivity C-reactive protein (hsCRP) and to evaluate their association with disease progression …
Iron overload induces cellular stress and is implicated in diverse pathological conditions. Nevertheless, the epigenetic mechanisms governing mammalian cellular responses to iron overload remain poorly characterized. Using multi-omics profiling in …
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to screen for embryo aneuploidy, enabling the selection and transfer of genetically normal embryos. Despite its potential to improve clinical outcomes, …
The study explored the mechanism of Dan'e-fukang soft extract in treating endometriosis (EMs) through network pharmacology. The main active ingredients of Dan'e-fukang soft extract were analyzed based on the traditional …
Botanical supplements are increasingly investigated for their potential to address women's health concerns. Compounds that modulate progesterone receptor (PR) signaling may help manage gynecologic disorders such as endometriosis, uterine hyperplasia, …
The purpose of this article is to provide a comprehensive review of recent literature addressing diagnoses and conditions that intersect pediatric and adolescent gynecology (PAG) and complex benign gynecology (CBG) …
The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for …
Endometriosis (EMS) is a chronic inflammatory disorder affecting ~10% of reproductive-age women, with increasing evidence implicating the microbiome in its pathogenesis through immunomodulation and estrogen metabolism. This study investigated microbiome …