Endometriosis is a chronic inflammatory, hormone dependent disorder that affects more than 200 million women worldwide. Immune dysfunction has emerged as one of the predominant mechanisms facilitating endometriosis lesion growth …
The endometrium is a highly dynamic and complex tissue lining the uterus, playing a central role in reproductive health. Despite its importance, the pathogenesis of many benign endometrial disorders remains …
Endometriosis affects 5-10% of reproductive-aged women and is characterized by chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility. Standard hormonal therapies, such as dienogest, effectively manage symptoms, but are often associated …
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare (prevalence ~ 1:2 million), devastating genetic disorder characterized by progressive heterotopic ossification. Crucially, surgical trauma is a potent trigger for catastrophic new bone …
Mid-life women are increasingly recognized as a vulnerable population for endocrine disruption due to chronic environmental exposures. Among emerging contaminants, per- and polyfluoroalkyl substances (PFAS) and microplastics have been implicated …
Intestinal endometriosis is a benign condition characterized by the presence of endometrial tissue within the bowel wall, often mimicking colorectal malignancy. Its coexistence with ulcerative colitis (UC) is rare and …
Mangroves are valuable reservoirs of diverse phytochemicals with significant therapeutic potential. Beyond their ecological roles, these bioactive compounds can influence epigenetic mechanisms, heritable changes in gene expression without alterations in …
Endometriosis is a common gynecological disorder affecting women of reproductive age, often leading to chronic pain, reduced quality of life, and infertility. It is characterized by ectopic endometrial growth within …
Traditional Chinese Medicine (TCM) offers multiple advantages in the treatment of endometriosis(EMS). Bushen Wenyang Huayu Decoction (BWHD) is widely used in clinical practice for managing EMS. It can significantly alleviate …
Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown.