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Quality of life identification by unsupervised cluster analysis: A new approach to modelling the burden of endometriosis.

Symptoms frequently associated with endometriosis affect quality of life (QoL). Our aim investigated the hypothesis that cluster analysis can be used to identify homogeneous phenotyping subgroups of women according to …

Published: Jan. 16, 2025, midnight
Endometriosis does not impact aneuploidy rates of products of conception in IVF population.

It has been debated whether endometriosis (EMS) adversely affects oocyte quality, potentially leading to a higher incidence of genetically unbalanced embryos or other egg factors that affect the developmental potential. …

Published: Jan. 16, 2025, midnight
New insights into the ferroptosis and immune infiltration in endometriosis: a bioinformatics-based analysis.

Ferroptosis, a recently discovered iron-dependent cell death, is linked to various diseases but its role in endometriosis is still not fully understood.

Published: Jan. 13, 2025, midnight
Endometriosis and risk of depression among oral contraceptive users: a pooled analysis of cohort studies from 13 countries.

Does endometriosis affect the mental health of women using oral contraceptives?

Published: Jan. 12, 2025, midnight
Single-cell and spatial transcriptomic profiling revealed niche interactions sustaining growth of endometriotic lesions.

Endometriosis is a chronic condition with limited therapeutic options. The molecular aberrations promoting ectopic attachment and interactions with the local microenvironment sustaining lesion growth have been unclear, prohibiting development of …

Published: Jan. 11, 2025, midnight
Validation of Tumor Budding as a Prognostic Factor in Ovarian Clear Cell Carcinoma Using an Independent Cohort.

Ovarian clear cell carcinoma (OCCC) is an endometriosis-related neoplasm, in which traditional histologic grading does not show prognostic significance. Tumor budding was associated with poorer outcomes in OCCC in previous …

Published: Jan. 10, 2025, midnight
Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions.

The mechanisms underlying the pathophysiology of endometriosis, characterized by the presence of endometrium-like tissue outside the uterus, remain poorly understood. This study aimed to identify cell type-specific gene expression changes …

Published: Jan. 10, 2025, midnight
Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS).

Progestogens commonly used in the clinic include levonorgestrel, etonogestrel, medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol. Progestogens are widely used for contraception and the treatment of endometriosis, threatened abortion and other …

Published: Jan. 8, 2025, midnight
Evaluating quality of life improvements in endometriosis patients following laparoscopic surgery using EHP-30 scale.

This study aims to evaluate whether laparoscopic surgery enhances health-related quality of life (HRQoL) in endometriosis patients, utilizing the Endometriosis Health Profile-30 (EHP-30) questionnaire. The study also explores the correlations …

Published: Jan. 7, 2025, midnight
A transcriptomic analysis of the interplay of ferroptosis and immune filtration in endometriosis and identification of novel therapeutic targets.

Endometriosis is an inflammatory disease, involving immune cell infiltration and production of inflammatory mediators. Ferroptosis has recently been recognized as a mode of controlled cell death and the iron overload …

Published: Jan. 7, 2025, midnight
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