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Association of elevated ACSL4 expression with impaired endometrial receptivity in endometriosis and restoration by ACSL4 inhibitor PRGL493.

This study investigated the role of ACSL4 in endometrial receptivity disorders in endometriosis (EMs) and evaluated PRGL493, an ACSL4 inhibitor, as a potential therapeutic target. Bioinformatic analysis identified ACSL4 as …

Published: July 27, 2025, midnight
Endometriosis-The scapegoat for pelvic pain?

Cyclic and noncyclic chronic pelvic pain (CPP) represent a major problem for both affected patients and healthcare providers due to its effects on physical and mental health. In times of …

Published: July 27, 2025, midnight
Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian Aging.

Organ functions generally decline with age, but the ovary is a prototypical organ that undergoes functional loss over time. Autophagy plays a crucial role in maintaining organ homeostasis, and age-related …

Published: July 27, 2025, midnight
The Prognosis of Endometriosis Correlates With Elevated Expression of LncRNA-ANRIL.

Background: Endometriosis is a chronic condition that affects the endometrium, the lining of the uterus. The endometrium typically thickens and discharges during the menstrual cycle, resulting in menstruation. Endometriosis is …

Published: July 26, 2025, midnight
The Impact of Targeted Endometriosis Treatment On Patients with Central Sensitization: Systematic Review and Meta Analysis.

Central sensitization (CSS), a condition where the central nervous system amplifies pain signals, may impact response to treatment of chronic pain conditions. The objective of this study is to determine …

Published: July 26, 2025, midnight
Endometriosis-Associated Periodontal Disease: A Large Cohort Perspective Study.

Endometriosis is a chronic estrogen-dependent gynecological disease affecting millions of women worldwide. Besides its well-established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. …

Published: July 26, 2025, midnight
Case Report: A Challenging Superior Hypogastric Plexus Block in a Patient with Enlarged and Bifid Transverse Processes.

Superior hypogastric plexus block (SHPB) is an established treatment for chronic pelvic pain (CPP). Anatomical variations can significantly complicate interventional pain procedures.

Published: July 26, 2025, midnight
MRI Versus Histopathology: Evaluating Diagnostic Accuracy in Detecting Endometrioma.

Introduction Endometriosis is a condition characterized by the presence of ectopic endometrial glands surrounded by endometrial stroma. When this occurs within the ovaries, it is referred to as an endometrioma. …

Published: July 25, 2025, midnight
The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
Associations between biological aging and the risk of endometriosis: Evidence from a large population-based prospective cohort study.

Endometriosis is a common disease for women of reproductive ages. Individuals with accelerated biological aging are at a higher risk of developing various diseases, however, the effect of biological aging …

Published: July 24, 2025, midnight
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