Endometriosis is a chronic, estrogen-dependent inflammatory disease that, despite its benign histology, displays several cancer-relevant features, including clonal expansion, somatic alteration-associated lesion evolution, tissue invasion, apoptosis resistance, immune evasion, angiogenesis, …
Endometriosis is a leading cause of chronic pelvic pain (CPP), but the public transcriptomic datasets analysed here contain no pain phenotype, links to CPP are therefore hypothesis-generating.
Endometriosis is a chronic inflammatory disorder affecting 5-10% of women of reproductive age and is associated with chronic pain and infertility. While research has mainly focused on local lesions, systemic …
The relationship between endometriosis and cardiovascular disease (CVD) risk remains unclear. This study aimed to evaluate the association between endometriosis and CVD risk, to examine whether the association was affected …
Endometriosis is a chronic inflammatory disease significantly impairing quality of life (QoL). While the Mediterranean diet (MD) may modulate inflammation, evidence regarding its relationship with symptom burden is limited. This …
Ovarian cancer remains one of the deadliest gynecologic malignancies because of late-stage diagnosis, biological heterogeneity, and the lack of effective early detection strategies. Epithelial ovarian cancer (EOC) comprises several histotypes, …
Pelvic magnetic resonance imaging (MRI) plays a pivotal role in evaluating gynecologic diseases, offering superior soft-tissue characterization, multiplanar imaging, and functional assessment compared to ultrasound and computed tomography. This article …
Endometriosis affects approximately 10% of reproductive-age women worldwide, with symptom burden significantly impacting quality of life. While current treatment guidelines focus primarily on hormonal and surgical interventions, the role of …
While negative neonatal outcomes are more frequent in fetuses with estimated fetal weight (EFW) < 10%, they also occur often in fetuses with appropriate-for-gestational-age. This study aimed to evaluate the …
Endometriosis is associated with immune dysregulation yet circulating cytokine measurements have shown limited discriminatory value. We investigated whether peripheral blood mononuclear cells (PBMCs) from women with endometriosis exhibit altered basal …