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Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This …

Published: April 27, 2026, midnight
NET-DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy-Mediated Anoikis Resistance in Endometriosis.

Endometriosis (EMs) features ectopic implantation of endometrial stromal cells (EESCs) and strong anoikis resistance, yet how inflammatory signals reprogram mitochondrial function remains unclear. Here, neutrophil extracellular traps (NETs), particularly their …

Published: April 27, 2026, midnight
Integrative gene ontology-driven analysis of the eutopic endometrium reveals key dysregulated functionomes and pathways in endometriosis.

Endometriosis is a chronic estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, and an increased risk of endometriosis-associated ovarian cancer. Despite extensive research, its molecular mechanisms remain incompletely understood. This …

Published: April 27, 2026, midnight
Nursing care for patients with endometriosis in Aotearoa New Zealand: a survey study.

Endometriosis is a chronic condition where patients face challenging care journeys. There is minimal literature regarding perspectives of nurses on their approach to caring for endometriosis patients.

Published: April 27, 2026, midnight
Evaluation of brain pain centers in endometriosis-associated chronic pelvic pain: Retrospective insights into central sensitization using a novel magnetic resonance imaging technique.

To investigate alterations in brain pain-processing networks using resting-state functional magnetic resonance imaging (rs-fMRI) in women with endometriosis-associated chronic pelvic pain and to evaluate neurobiological evidence of central sensitization relevant …

Published: April 25, 2026, midnight
A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.

Chronic pelvic pain is one of the most prevalent syndromes in family medicine, gynecology, and urology. Chronic pelvic pain patients are often misdiagnosed and have unnecessary prolonged suffering. Both misdiagnosis …

Published: April 25, 2026, midnight
Microbiota-metabolite axis in endometriosis: Pathogenic mechanisms and clinical implications.

Growing evidence highlights the role of microbiota, including those of the gut, reproductive tract, and endometrial tissue, as critical functional drivers in the pathogenesis of endometriosis (EM). Studies have revealed …

Published: April 25, 2026, midnight
The impact of endometriosis on long-term neurologic morbidity of the offspring: a population-based analysis.

Endometriosis, a chronic inflammatory disease, has been associated with adverse pregnancy and perinatal outcomes, which in turn have been linked to long-term neurological morbidity in the offspring. This study aimed …

Published: April 25, 2026, midnight
Effect of postoperative hormonal therapy on pain following endometriosis surgery: a retrospective cohort study.

Endometriosis is heterogeneous, and evidence for individualised postoperative management is limited. We assessed whether postoperative hormonal therapy exposure is associated with one-year changes in pain domains after first-time endometriosis surgery …

Published: April 24, 2026, midnight
Detection of Activin A and Follistatin as Potential Biomarkers in Women with Ovarian Endometriosis.

Endometriosis is a condition characterized by the growth of tissue similar to the uterine lining outside the uterus. This study aimed to evaluate certain sex hormones and determine the levels …

Published: April 24, 2026, midnight
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