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Bioinformatic analysis and validation of candidate genes in the eutopic endometrium reveal differential expressions in diffuse adenomyosis, endometrioma, and their co-existence.

Adenomyosis and endometriosis are hormone-dependent benign gynecological disorders with overlapping features suggesting that they may share a common origin despite being considered distinct entities. This study compares the expression of …

Published: Nov. 21, 2025, midnight
Long-term risk of psychiatric disorders in women with endometriosis: A retrospective cohort study.

Endometriosis is a chronic, estrogen-dependent condition associated with substantial physical and psychological burden. Although psychiatric comorbidities are frequently reported, large-scale real-world data remain limited.

Published: Nov. 21, 2025, midnight
The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies.

Mitophagy is a catabolic mechanism that selectively degrades damaged mitochondria and precisely modulates mitochondrial content, thereby maintaining intracellular homeostasis under stress conditions. To date, most reviews on mitophagy have predominantly …

Published: Nov. 18, 2025, midnight
Gene regulation by non-Coding RNAs in infertility: a mechanistic review.

Infertility is a significant global health issue affecting millions of couples, with noncoding RNAs (ncRNAs) emerging as pivotal regulators in reproductive biology. This review explores the roles of various ncRNAs, …

Published: Nov. 17, 2025, midnight
How We Can Optimize Dysmenorrhea Treatment: Real-World Results from a Cross-Sectional, Multi-Center Study.

Dysmenorrhea is a common and disabling condition in women. We investigate the prevalence of endocrine dysmenorrhea treatment (EDT) and the use of pain medication in dysmenorrhea patients without surgically treated …

Published: Nov. 17, 2025, midnight
Causal associations between sleep disorders and endometriosis: A Mendelian randomization analysis.

Evidence have indicated a correlation between sleep disorders and endometriosis, but the causal relationship remains uncertain. This study utilized Mendelian randomization (MR) approach to investigate the causal associations between sleep …

Published: Nov. 10, 2025, midnight
Sexual function and sexual quality of life in women affected by endometriosis and adenomyosis compared to healthy women.

Adenomyosis and endometriosis are chronic gynecological disorders with overlapping mechanisms and symptoms, both linked to impaired sexual health and relationships. This study compared sexual function, sexual quality of life, and …

Published: Nov. 10, 2025, midnight
Spontaneous Pneumothorax: A Review of Underlying Etiologies and Diagnostic Imaging Modalities.

This review focuses on the diverse etiologies of secondary spontaneous pneumothorax (SSP) and the crucial role of imaging in their diagnosis. Unlike primary spontaneous pneumothorax (PSP), which is typically due …

Published: Nov. 7, 2025, midnight
Ferroptosis in reproductive system disorders: Pathological roles and therapeutic potential.

Ferroptosis, as an iron-dependent programmed cell death, plays a significant role in reproductive system diseases. It's involved in the pathological processes of various reproductive system diseases by affecting the survival …

Published: Nov. 5, 2025, midnight
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