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E2F1 downregulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.

Endometriosis is a common gynecological disease in which lipid metabolic dysregulation has been increasingly implicated. However, the specific metabolic changes in ectopic lesions and stromal cells remain poorly understood. It …

Published: Sept. 28, 2026, midnight
Transvaginal Strain Elastography Methodology in Deep Endometriosis: Narrative Review and Proposal of a Standardized Imaging Protocol.

Transvaginal strain elastography (SE) has emerged as a complementary technique to transvaginal ultrasound for deep endometriosis (DE) evaluation by exploiting tissue stiffness between lesions and surrounding structures. However, its clinical …

Published: Sept. 28, 2026, midnight
Use of symptom-reporting tools to support endometriosis identification and management in primary care: a realist synthesis.

Endometriosis affects 5-10% of women of reproductive age and is associated with chronic pain, infertility and reduced quality of life. Symptom Reporting Tools (SRTs) may support identification and management in …

Published: Sept. 28, 2026, midnight
Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation.

Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …

Published: Sept. 28, 2026, midnight
HIV funding squeeze deepens as US commits $887m to DRC Ebola response - standardmedia.co.ke

HIV funding squeeze deepens as US commits $887m to DRC Ebola response standardmedia.co.ke

Published: Sept. 27, 2026, 9:53 a.m.
Ten missing on Nepal's Himlung peak after avalanche - standardmedia.co.ke

Ten missing on Nepal's Himlung peak after avalanche standardmedia.co.ke

Published: Sept. 27, 2026, 9:49 a.m.
A Case of Deep Infiltrating Endometriosis Undergoing Malignant Transformation to Müllerian Adenosarcoma: Case Report and Literature Review.

Müllerian adenosarcoma (MA) is a rare malignant tumor of the female reproductive system. Owing to the limited number of clinical cases and the absence of characteristic clinical manifestations, its clinical …

Published: Sept. 27, 2026, midnight
Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report.

Malignant transformation of endometriosis is rare and most commonly involves the ovary; transformation from paraurethral endometriosis is exceedingly rare.

Published: Sept. 27, 2026, midnight
Simvastatin and Primaquine Identified as Potential Endometriosis Therapeutics via a Novel Epithelial-Stromal Assembloid Drug Screening Assay.

Endometriosis is an estrogen-driven, inflammatory disorder affecting ~10% of menstruators, causing severe pain. Current treatments that reduce estrogen or inflammation have inconsistent efficacy and poor tolerability. Therapies identified via drug-repositioning …

Published: Sept. 27, 2026, midnight
British couples left tens of thousands of pounds out of pocket after IVF clinic goes bust - The Independent

British couples left tens of thousands of pounds out of pocket after IVF clinic goes bust The Independent

Published: Sept. 26, 2026, 9:43 a.m.
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